Evidence map›Paper›PMID 35360848›Full record

ArticleFrontiers in genetics2022

Case Report: Preimplantation Genetic Testing for Meckel Syndrome Induced by Novel Compound Heterozygous Mutations of

Tingting Lin, Yongyi Ma, Danni Zhou, Liwei Sun, Ke Chen, Yezhou Xiang, Keya Tong, Chaoli Jia, Kean Jiang, Dongyun Liu and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Novel homozygous mutations in TXNDC15 causing Meckel syndrome.Molecular genetics & genomic medicine · 2024
    Article
  3. Identification of novelFrontiers in genetics · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Tingting LinChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Yongyi MaThe Southwest Hospital of Army Medical University, Chongqing, China.
Danni ZhouChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Liwei SunChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Ke ChenChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Yezhou XiangChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Keya TongChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Chaoli JiaChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Kean JiangChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Dongyun LiuChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Guoning HuangChongqing Key Laboratory of Human Embryo Engineering, Chongqing, China.
Chongqing Maternal and Child Health Hospital · CNArmy Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meckel syndrome (MKS), also known as the Meckel-Gruber syndrome, is a severe pleiotropic autosomal recessive developmental disorder caused by dysfunction of the primary cilia during early embryogenesis. The diagnostic criteria are based on clinical variability and genetic heterogeneity. Mutations in the

Indexed as

exon skipping variantintron mutationMeckel syndromeMKS1 genePGT-M

Identifiers

PMID35360848
PMCPMC8963843
OpenAlexW4220786258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.