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ArticleFrontiers in medicine2022

Who Is at Risk of Poor Mental Health Following Coronavirus Disease-19 Outpatient Management?

Katharina Hüfner, Piotr Tymoszuk, Dietmar Ausserhofer, Sabina Sahanic, Alex Pizzini, Verena Rass, Matyas Galffy, Anna Böhm, Katharina Kurz, Thomas Sonnweber and 12 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04661462 (Health After COVID-19 in the European Region Tyrol - South Tyrol), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04661462 unknown statusnot on this map

Health After COVID-19 in the European Region Tyrol - South Tyrol

TypeobservationalSponsorMedical University InnsbruckRan2020 to 2021Enrolled1,000ConditionsCOVID-19Armsonline survey
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. The long COVID and its mental health manifestations - the review of literature.International journal of occupational medicine and environmental health · 2024
    Review
  6. Persistence of symptoms and lung function in mild cases of COVID-19 six months after infection: a cross-sectional study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Article
  7. Article
  8. Complex association between post-COVID-19 condition and anxiety and depression symptoms.European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Article
  9. Article
  10. Article
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  12. Article
  13. Article
  14. Brain Fog and Quality of Life at Work in Non-Hospitalized Patients after COVID-19.International journal of environmental research and public health · 2022
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 2 countries.

Katharina HüfnerDepartment of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Hospital for Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria.
Piotr TymoszukData Analytics as a Service Tirol, Innsbruck, Austria.
Dietmar AusserhoferInstitute of General Practice and Public Health, Claudiana Bolzano, Bolzano, Italy.
Sabina SahanicDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Alex PizziniDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Verena RassDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Matyas GalffyDepartment of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Hospital for Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria.
Anna BöhmDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Katharina KurzDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Thomas SonnweberDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Ivan TancevskiDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Stefan KiechlDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Andreas HuberTyrolean Federal Institute for Integrated Care, Innsbruck, Austria.
Barbara PlaggInstitute of General Practice and Public Health, Claudiana Bolzano, Bolzano, Italy.
Christian J WiedermannInstitute of General Practice and Public Health, Claudiana Bolzano, Bolzano, Italy.
Rosa Bellmann-WeilerDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Herbert BachlerInstitute of General Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Günter WeissDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Giuliano PiccolioriInstitute of General Practice and Public Health, Claudiana Bolzano, Bolzano, Italy.
Raimund HelbokDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Judith Loeffler-RaggDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Barbara Sperner-UnterwegerDepartment of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Hospital for Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · ATUniversität Innsbruck · ATOspedale di Bolzano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronavirus Disease-19 (COVID-19) convalescents are at risk of developing a Methods: We conducted a binational online survey study with adult non-hospitalized COVID-19 convalescents (Austria/AT: Results: Depression and/or anxiety before infection was reported by 4.6% (IT)/6% (AT) of participants. At a median of 79 days (AT)/96 days (IT) post-COVID-19 onset, 12.4% (AT)/19.3% (IT) of subjects were screened positive for anxiety and 17.3% (AT)/23.2% (IT) for depression. Over one-fifth of the respondents rated their OMH (AT: 21.8%, IT: 24.1%) or QoL (AT: 20.3%, IT: 25.9%) as fair or poor. Psychosocial stress, physical performance loss, high numbers of acute and sub-acute COVID-19 complaints, and the presence of acute and sub-acute neurocognitive symptoms (impaired concentration, confusion, and forgetfulness) were the strongest correlates of deteriorating mental health and poor QoL. In clustering analysis, these variables defined subsets with a particularly high propensity of post-COVID-19 mental health impairment and decreased QoL. Pre-existing depression or anxiety (DA) was associated with an increased symptom burden during acute COVID-19 and recovery. Conclusion: Our study revealed a bidirectional relationship between COVID-19 symptoms and mental health. We put forward specific acute symptoms of the disease as "red flags" of mental health deterioration, which should prompt general practitioners to identify non-hospitalized COVID-19 patients who may benefit from early psychological and psychiatric intervention. Clinical Trial Registration: [ClinicalTrials.gov], identifier [NCT04661462].

Indexed as

anxietyCOVID-19depressionlong COVIDmachine learningmental stressneurocognitiveSARS-CoV-2

Identifiers

PMID35360744
PMCPMC8964263
OpenAlexW4221119295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.