Evidence map›Paper›PMID 35360574›Full record

ArticleFrontiers in psychology2022

C-Reactive Protein and TGF-α Predict Psychological Distress at Two Years of Follow-Up in Healthy Adolescent Boys: The Fit Futures Study.

Jonas Linkas, Luai Awad Ahmed, Gabor Csifcsak, Nina Emaus, Anne-Sofie Furberg, Guri Grimnes, Gunn Pettersen, Kamilla Rognmo, Tore Christoffersen

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jonas LinkasDepartment of Health and Care Sciences, UiT The Arctic University of Norway, Narvik, Norway.
Luai Awad AhmedInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Gabor CsifcsakDepartment of Psychology, UiT The Arctic University of Norway, Tromsø, Norway.
Nina EmausDepartment of Health and Care Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
Anne-Sofie FurbergFaculty of Health and Care Sciences, Molde University College, Molde, Norway.
Guri GrimnesDivision of Internal Medicine, University Hospital of North Norway, Tromsø, Norway.
Gunn PettersenDepartment of Health and Care Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
Kamilla RognmoDepartment of Psychology, UiT The Arctic University of Norway, Tromsø, Norway.
Tore ChristoffersenDepartment of Health and Care Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
UiT The Arctic University of Norway · NOMolde University College · NOUnited Arab Emirates University · AEUniversity Hospital of North Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The scarcity of research on associations between inflammatory markers and symptoms of depression and anxiety during adolescence has yielded inconsistent results. Further, not all studies have controlled for potential confounders. We explored the associations between baseline inflammatory markers and psychological distress including moderators at follow-up in a Norwegian adolescent population sample. Methods: Data was derived from 373 girls and 294 boys aged 15-18 years at baseline, in the Fit Futures Study, a large-scale 2-year follow-up study on adolescent health. Baseline data was gathered from 2010 to 2011 and follow-up data from 2012 to 2013. Psychological distress was measured with Hopkins Symptom Checklist (HSCL-10). Serum levels of the following inflammatory markers were measured: C-reactive protein (CRP), Interleukin 6 (IL-6), Transforming growth factor alpha (TGF-α), Tumor necrosis factor alpha variant 1 (TRANCE), and variant 2 (TWEAK). Independent associations between baseline inflammatory markers and HSCL-10 at follow-up were explored by linear regressions, in sex-stratified analyses. Results: In girls, analyses showed positive associations between all inflammatory markers and HSCL-10, except for TRANCE. However, all associations were non-significant in crude as well as in adjusted analyses. In boys, CRP ( Conclusion: There were significant prospective associations between CRP, TFG-α, and HSCL-10 in boys aged 15-18 years at baseline.

Indexed as

adolescenceanxiety symptomsdepressive symptomsinflammatory markerspsychological distress

Identifiers

PMID35360574
PMCPMC8963454
OpenAlexW4220868780

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.