Evidence map›Paper›PMID 35360458›Full record

ArticleCase reports in hematology2022

Pure White Cell Aplasia and Immune Thrombocytopenia after Thymoma Resection: A Case Report and Review of the Literature.

Michael Youssef, Tyler W Stratton, Reid C Gallant, Christine Young, Daniel Y Li, Siavash Piran

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Michael YoussefFaculty of Medicine, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0001-8463-6601
Tyler W StrattonSchulich School of Medicine & Dentistry, Western University, London, ON, Canada.ORCID https://orcid.org/0000-0001-6134-6804
Reid C GallantFaculty of Medicine, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0002-9730-4427
Christine YoungDepartment of Pharmacy, Trillium Health Partners, Mississauga, Ontario, Canada.
Daniel Y LiDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.
Siavash PiranDepartment of Medicine, Division of Hematology, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0002-5052-9418
University of Toronto · CATrillium Health Centre · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of pure white cell aplasia (PWCA) postthymoma resection in a 74-year-old male presenting with a 2-week history of fevers, night sweats, and severe febrile neutropenia. His pure white cell aplasia was treated with intravenous immunoglobulin (IVIg), granulocyte colony-stimulating factor (G-CSF), prednisone, and cyclosporine with a mixed response. He also developed immune thrombocytopenia, which responded well to a short course of eltrombopag. With continued cyclosporine treatment, his platelet counts were stable after stopping eltrombopag. The patient's cyclosporine treatment was complicated by renal failure, resulting in cessation of cyclosporine. His PWCA and immune thrombocytopenia significantly worsened after stopping cyclosporine, and unfortunately, he died from multiorgan failure and sepsis.

Identifiers

PMID35360458
PMCPMC8964212
OpenAlexW4221058872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.