Evidence map›Paper›PMID 35360409›Full record

ArticleBMJ neurology open2022

Comparison of diabetic and idiopathic sensory polyneuropathies with respect to nerve fibre affection and risk factors.

Mustapha Itani, Sif Gylfadottir, Thomas Krøigård, Laura Gaist, Jakob Vormstrup Holbech, Alexander Gramm Kristensen, Pall Karlsson, Sören Möller, Hatice Tankisi, David Gaist and 3 more

Open access · diamondAbstract read
In one paragraph

Article in BMJ neurology open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Mustapha ItaniResearch Unit for Neurology, Department of Neurology, Odense University Hospital, Odense, Denmark.ORCID 0000-0001-6936-8493
Sif GylfadottirDanish Pain Research Center, Clinical Medicine, Aarhus University, Aarhus, Denmark.
Thomas KrøigårdResearch Unit for Neurology, Department of Neurology, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-1565-6948
Laura GaistResearch Unit for Neurology, Department of Neurology, Odense University Hospital, Odense, Denmark.
Jakob Vormstrup HolbechResearch Unit for Neurology, Department of Neurology, Odense University Hospital, Odense, Denmark.
Alexander Gramm KristensenClinical Neurophysiology, Aarhus Universitetshospital, Aarhus, Denmark.
Pall KarlssonDanish Pain Research Centre, Department of Clinical Medicine, Core Center for Molecular Morphology, Aarhus Universitet, Aarhus, Denmark.
Sören MöllerOPEN, Odense University Hospital, Odense, Denmark.
Hatice TankisiClinical Neurophysiology, Aarhus Universitetshospital, Aarhus, Denmark.
David GaistResearch Unit for Neurology, Department of Neurology, Odense University Hospital, Odense, Denmark.
Troels S JensenDanish Pain Research Center, Clinical Medicine, Aarhus University, Aarhus, Denmark.
Nanna Brix FinnerupNeurology, Aarhus Universitetshospital, Aarhus, Denmark.
Søren Hein SindrupResearch Unit for Neurology, Department of Neurology, Odense University Hospital, Odense, Denmark.
Aarhus University · DKUniversity of Southern Denmark · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Chronic distal sensory or sensorimotor polyneuropathy is the most common pattern of polyneuropathy. The cause of this pattern is most often diabetes or unknown. This cross-sectional study is one of the first studies to compare the demographics, cardiovascular risk factors and clinical characteristics of diabetic polyneuropathy (DPN) with idiopathic polyneuropathy (IPN). Methods: Patients with DPN were included from a sample of 389 patients with type 2 diabetes mellitus (T2DM) enrolled from a national cohort of patients with recently diagnosed T2DM (Danish Centre for Strategic Research in Type 2 Diabetes cohort). Patients with IPN were included from a regional cohort of patients with symptoms of polyneuropathy referred for workup at a combined secondary and tertiary neurological centre (database cohort). Results: A total of 214 patients with DPN were compared with a total of 88 patients with IPN. Patients with DPN were older (67.4 vs 59 years) and had a longer duration of neuropathy symptoms. Patients with DPN had greater body mass index (32 vs 27.4 kg/m Conclusion: DPN and IPN showed clear differences in neuropathy characteristics, indicating that these two entities are to be regarded as aetiologically and pathogenetically distinct.

Indexed as

diabetesdiabetic neuropathyneuropathyneurophysiol, clinicaL

Identifiers

PMID35360409
PMCPMC8921860
OpenAlexW4221022888

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.