Evidence map›Paper›PMID 35360391›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Human Organ-on-a-Chip Microphysiological Systems to Model Musculoskeletal Pathologies and Accelerate Therapeutic Discovery.

Raquel E Ajalik, Rahul G Alenchery, John S Cognetti, Victor Z Zhang, James L McGrath, Benjamin L Miller, Hani A Awad

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  12. Tissue chips as headway model and incitement technology.Synthetic and systems biotechnology · 2025
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raquel E AjalikCenter for Musculoskeletal Research, University of Rochester, Rochester, NY, United States.
Rahul G AlencheryCenter for Musculoskeletal Research, University of Rochester, Rochester, NY, United States.
John S CognettiDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Victor Z ZhangCenter for Musculoskeletal Research, University of Rochester, Rochester, NY, United States.
James L McGrathDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Benjamin L MillerDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Hani A AwadCenter for Musculoskeletal Research, University of Rochester, Rochester, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Microphysiological Systems (hMPS), otherwise known as organ- and tissue-on-a-chip models, are an emerging technology with the potential to replace

Indexed as

bonecartilagemicrophysiologic systemsmusclemusculoskeletalorgan-on-chiptendon and ligamenttissue-on-chip

Identifiers

PMID35360391
PMCPMC8964284

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.