Evidence map›Paper›PMID 35360386›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Decellularization of Wharton's Jelly Increases Its Bioactivity and Antibacterial Properties.

M Dubus, L Scomazzon, J Chevrier, A Montanede, A Baldit, C Terryn, F Quilès, C Thomachot-Schneider, S C Gangloff, N Bouland and 4 more

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

M DubusBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.
L ScomazzonBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.
J ChevrierBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.
A MontanedeBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.
A BalditLaboratoire d'étude des Microstructures et de Mécanique des Matériaux (LEM3), UMR CNRS 7239, Université de Lorraine, Metz, France.
C TerrynPlateau Technique PICT, Université de Reims Champagne Ardenne, Reims, France.
F QuilèsCNRS, LCPME, Université de Lorraine, Nancy, France.
C Thomachot-SchneiderGroupe d'Étude des Géomatériaux et Environnement Naturels, Anthropiques et Archéologiques (GEGENAA), Université de Reims Champagne Ardenne, Reims, France.
S C GangloffBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.
N BoulandService d'anatomopathologie, UFR de Médecine, Université de Reims Champagne Ardenne, Reims, France.
F GindrauxLaboratoire de Nanomédecine, Imagerie, Thérapeutique, Université Bourgogne Franche-Comté, Besançon, France.
H RammalBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.
C MauprivezBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.
H KerdjoudjBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, Reims, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of regenerative medicine has recently seen an emerging trend toward decellularized extracellular matrix (ECM) as a biological scaffold for stem cell-delivery. Human umbilical cord represents a valuable opportunity from both technical and ethical point of view to obtain allogenic ECM. Herein, we established a protocol, allowing the full removal of cell membranes and nuclei moieties from Wharton's jelly (WJ) tissue. No alterations in the ECM components (

Indexed as

antibacterialbioactivitybiocompatibilitydecellularizationin vivoWharton’s jelly

Identifiers

PMID35360386
PMCPMC8963334

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.