Evidence map›Paper›PMID 35360241›Full record

ArticleFrontiers in physiology2022

Physiological Responses to Acute Cycling With Blood Flow Restriction.

Matthew A Kilgas, Tejin Yoon, John McDaniel, Kevin C Phillips, Steven J Elmer

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07668921 (Blood Flow Restriction), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07668921 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Blood Flow Restriction (BFR): a Novel Approach to Potentiate the Effects of Rehabilitative Exercise Training in COPD? Study of Acute - Muscular, and Vascular - Responses to a Single Session of Exercise With BFR

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2026 to 2028Enrolled40ConditionsControl Condition, Pulmonary Disease (COPD), Chronic Obstructive, Blood Flow Restriction Training (BFRT)ArmsBlood Flow Restriction, Standard exercise session
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

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  5. Article
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  11. Hemodynamic analysis of blood flow restriction training: a systematic review.BMC sports science, medicine & rehabilitation · 2025
    Article
  12. Article
  13. Tourniquet cuff pressure during blood flow restriction exercise.Frontiers in sports and active living · 2025
    Article
  14. Article
  15. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Matthew A KilgasSchool of Health and Human Performance, Northern Michigan University, Marquette, MI, United States.
Tejin YoonDepartment of Physical Education, Kangwon National University, Chuncheon, South Korea.
John McDanielDepartment of Exercise Physiology, Kent State University, Kent, OH, United States.
Kevin C PhillipsDepartment of Kinesiology and Integrative Physiology, Michigan Technological University, Houghton, MI, United States.
Steven J ElmerDepartment of Kinesiology and Integrative Physiology, Michigan Technological University, Houghton, MI, United States.
Michigan Technological University · USKangwon National University · KRKent State University · USNorthern Michigan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aerobic exercise with blood flow restriction (BFR) can improve muscular function and aerobic capacity. However, the extent to which cuff pressure influences acute physiological responses to aerobic exercise with BFR is not well documented. We compared blood flow, tissue oxygenation, and neuromuscular responses to acute cycling with and without BFR. Ten participants completed four intermittent cycling (6 × 2 min) conditions: low-load cycling (LL), low-load cycling with BFR at 60% of limb occlusion pressure (BFR60), low-load cycling with BFR at 80% of limb occlusion pressure (BFR80), and high-load cycling (HL). Tissue oxygenation, cardiorespiratory, metabolic, and perceptual responses were assessed during cycling and blood flow was measured during recovery periods. Pre- to post-exercise changes in knee extensor function were also assessed. BFR60 and BFR80 reduced blood flow (~33 and ~ 50%, respectively) and tissue saturation index (~5 and ~15%, respectively) when compared to LL (all

Indexed as

aerobic exercisearterial blood flowfatiguefunctional near inferred spectroscopyKaatsuvascular occlusion

Identifiers

PMID35360241
PMCPMC8963487
OpenAlexW4220855258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.