Evidence map›Paper›PMID 35360212›Full record

ArticleFrontiers in aging neuroscience2022

Effect of 3-Month Aerobic Dance on Hippocampal Volume and Cognition in Elderly People With Amnestic Mild Cognitive Impairment: A Randomized Controlled Trial.

Yi Zhu, Yaxin Gao, Chuan Guo, Ming Qi, Ming Xiao, Han Wu, Jinhui Ma, Qian Zhong, Hongyuan Ding, Qiumin Zhou and 9 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06644690 (The Effect of a Creative Dance-Supported CO-OP Approach on Executive Functions, Attention, Memory, and Dual-Task Performance in Older Adults With Mild Cognitive Impairment), which is not on this map. Cited by 27 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 11 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06644690 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effect of a Creative Dance-Supported CO-OP Approach on Executive Functions, Attention, Memory, and Dual-Task Performance in Older Adults With Mild Cognitive Impairment: A Randomized Controlled Trial

TypeinterventionalSponsorÇankırı Karatekin UniversityRan2024 to 2025Enrolled26ConditionsMild Cognitive Impairment (MCI)ArmsCO-OP with Creative Dance, CO-OP Only
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 11 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Yi ZhuRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yaxin GaoRehabilitation Medicine Center, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Chuan GuoRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ming QiDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ming XiaoJiangsu Key Laboratory of Neurodegeneration, Center for Global Health, Nanjing Medical University, Nanjing, China.
Han WuRehabilitation Department, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Jinhui MaDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Qian ZhongRehabilitation Department, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Hongyuan DingDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qiumin ZhouRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nawab AliFirst School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Li ZhouRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qin ZhangRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ting WuDepartment of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wei WangDepartment of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cuiyun SunRehabilitation Department, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Lehana ThabaneDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Ling ZhangDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Tong WangRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNNanjing Medical University · CNNanjing Drum Tower Hospital · CNImpact · CAMcMaster University · CASuzhou Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an intermediate state between normal aging and dementia, mild cognitive impairment (MCI), especially amnestic MCI (aMCI), is a key stage in the prevention and intervention of Alzheimer's disease (AD). Whether dancing could increase the hippocampal volume of seniors with aMCI remains debatable. The aim of this study was to investigate the influence of aerobic dance on hippocampal volume and cognition after 3 months of aerobic dance in older adults with aMCI. In this randomized controlled trial, 68 elderly people with aMCI were randomized to either the aerobic dance group or the control group using a 1:1 allocation ratio. Ultimately, 62 of 68 participants completed this study, and the MRI data of 54 participants were included. A specially designed aerobic dance routine was performed by the dance group three times per week for 3 months, and all participants received monthly healthcare education after inclusion. MRI with a 3.0T MRI scanner and cognitive assessments were performed before and after intervention. High-resolution three-dimensional (3D) T1-weighted anatomical images were acquired for the analysis of hippocampal volume. A total of 35 participants (mean age: 71.51 ± 6.62 years) were randomized into the aerobic dance group and 33 participants (mean age: 69.82 ± 7.74 years) into the control group. A multiple linear regression model was used to detect the association between intervention and the difference of hippocampal volumes as well as the change of cognitive scores at baseline and after 3 months. The intervention group showed greater right hippocampal volume (β [95% CI]: 0.379 [0.117, 0.488],

Indexed as

cognitioncognitive impairmentdancinghippocampusmotor cognitive training

Identifiers

PMID35360212
PMCPMC8961023
OpenAlexW4221131496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.