Evidence map›Paper›PMID 35360209›Full record

ArticleFrontiers in aging neuroscience2022

Transcranial Direct Current Stimulation May Reduce Prefrontal Recruitment During Dual Task Walking in Functionally Limited Older Adults - A Pilot Study.

Azizah J Jor'dan, Hagar Bernad-Elazari, Anat Mirelman, Natalia A Gouskova, On-Yee Lo, Jeffrey M Hausdorff, Brad Manor

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Modulating Brain Activity to Improve Goal-directed Physical Activity in Older Adults: A Pilot Randomized Controlled Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Trial
  5. Trial
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Azizah J Jor'danDepartment of Exercise and Health Sciences, University of Massachusetts Boston, Boston, MA, United States.
Hagar Bernad-ElazariCenter for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Anat MirelmanCenter for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Natalia A GouskovaHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
On-Yee LoHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
Jeffrey M HausdorffCenter for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Brad ManorHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
Hebrew SeniorLife · USTel Aviv Sourasky Medical Center · ILRush University Medical Center · US

Funding

Vascular mechanisms and tDCS treatment of gait and posture in aging and age-related diseasesR00AG051766 · NIA · UNIVERSITY OF MASSACHUSETTS BOSTON · PI JOR'DAN, AZIZAH J. · 2020 to 2022
$737k
Modulating brain networks to reduce gait variability in older adults at risk of fallingK01AG075252 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI CARRETIE, SABRINA, LO, ON-YEE AMY · 2022 to 2024
$362k
Vascular mechanisms and tDCS treatment of gait and posture in aging and age-related diseaseK99AG051766 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI JOR'DAN, AZIZAH J. · 2017 to 2018
$259k
NIA NIH HHS K01 AG075252NIA NIH HHS K99 AG051766NIA NIH HHS R00 AG051766
6 · The paper itself

Abstract

Introduction: Transcranial direct current stimulation (tDCS) targeting the left dorsolateral prefrontal cortex (dlPFC) improves dual task walking in older adults, when tested just after stimulation. The acute effects of tDCS on the cortical physiology of walking, however, remains unknown. Methods: In a previous study, older adults with slow gait and executive dysfunction completed a dual task walking assessment before and after 20 min of tDCS targeting the left dlPFC or sham stimulation. In a subset of seven participants per group, functional near-infrared spectroscopy (fNIRS) was used to quantify left and right prefrontal recruitment defined as the oxygenated hemoglobin response to usual and dual task walking (ΔHbO2), as well as the absolute change in this metric from usual to dual task conditions (i.e., ΔHbO2 Results: The tDCS group exhibited pre- to post-stimulation reduction in left prefrontal ΔHbO2 Discussion: This preliminary fNIRS data suggests that tDCS over the left dlPFC may modulate prefrontal recruitment, as reflected by a relative reduction in the oxygen consumption of this brain region in response to dual task walking.

Indexed as

brain stimulationfNIRSgaitneural efficiencyoxygenated hemoglobin

Identifiers

PMID35360209
PMCPMC8963782
OpenAlexW4220815374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.