ArticleFrontiers in neuroscience2022
Increased Excursions to Functional Networks in Schizophrenia in the Absence of Task.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Salience Network Dynamics Across Spontaneous Attacks, Interictal Rest and Interictal Pain Imagery in Menstrually Related Migraine.Brain topography · 2026Article
- Dynamic Repertoire of Brain Networks in Mindfulness-Based Cognitive Therapy During Rumination: A Randomized Controlled Trial.Biological psychiatry global open science · 2026Article
- Cortical synchrony is reduced in Alzheimer's disease and relates to arousal state.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Energy-Based Phase-Locking State Analysis in Brain State Identification.Human brain mapping · 2026Article
- Task-related differences in network connectivity and dynamics in people with severe opioid use disorder compared with healthy controls.Translational psychiatry · 2026Article
- Decoding Schizophrenia: How AI-Enhanced fMRI Unlocks New Pathways for Precision Psychiatry.Brain sciences · 2024Article
- Abnormal Dynamic Reconstruction of Overlapping Communities in Schizophrenia Patients.Brain sciences · 2024Article
- Insomnia disorder characterized by probabilistic metastable substates using blood-oxygenation-level-dependent (BOLD) phase signals.Sleep & breathing = Schlaf & Atmung · 2024Article
- Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation.PLoS computational biology · 2024Article
- Inducing a meditative state by artificial perturbations: A mechanistic understanding of brain dynamics underlying meditation.Network neuroscience (Cambridge, Mass.) · 2024Article
- Challenges in the measurement and interpretation of dynamic functional connectivity.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Long-term mindfulness meditation increases occurrence of sensory and attention brain states.Frontiers in human neuroscience · 2024Article
- Leveraging multi-echo EPI to enhance BOLD sensitivity in task-based olfactory fMRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Depression recurrence is accompanied by longer periods in default mode and more frequent attentional and reward processing dynamic brain-states during resting-state activity.Human brain mapping · 2023Article
- A phenomenological model of whole brain dynamics using a network of neural oscillators with power-coupling.Scientific reports · 2023Article
- Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness.NeuroImage · 2023Article
- Article
- Metastability, fractal scaling, and synergistic information processing: What phase relationships reveal about intrinsic brain activity.NeuroImage · 2022Article
- Frequency-Specific Analysis of the Dynamic Reconfiguration of the Brain in Patients with Schizophrenia.Brain sciences · 2022Article
- Alteration of resting-state network dynamics in autism spectrum disorder based on leading eigenvector dynamics analysis.Frontiers in integrative neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schizophrenia is a chronic psychotic disorder characterized by the disruption of thought processes, perception, cognition, and behaviors, for which there is still a lack of objective and quantitative biomarkers in brain activity. Using functional magnetic resonance imaging (fMRI) data from an open-source database, this study investigated differences between the dynamic exploration of resting-state networks in 71 schizophrenia patients and 74 healthy controls. Focusing on recurrent states of phase coherence in fMRI signals, brain activity was examined for intergroup differences through the lens of dynamical systems theory. Results showed reduced fractional occupancy and dwell time of a globally synchronized state in schizophrenia. Conversely, patients exhibited increased fractional occupancy, dwell time and limiting probability of being in states during which canonical functional networks-i.e., Limbic, Dorsal Attention and Somatomotor-synchronized in anti-phase with respect to the rest of the brain. In terms of state-to-state transitions, patients exhibited increased probability of switching to Limbic, Somatomotor and Visual networks, and reduced probability of remaining in states related to the Default Mode network, the Orbitofrontal network and the globally synchronized state. All results revealed medium to large effect sizes. Combined, these findings expose pronounced differences in the temporal expression of resting-state networks in schizophrenia patients, which may relate to the pathophysiology of this disorder. Overall, these results reinforce the utility of dynamical systems theory to extend current knowledge regarding disrupted brain dynamics in psychiatric disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.