Evidence map›Paper›PMID 35360165›Full record

ArticleFrontiers in neuroscience2022

Dual Roles of Coconut Oil and Its Major Component Lauric Acid on Redox Nexus: Focus on Cytoprotection and Cancer Cell Death.

Venkatesan Ramya, Karuppiah Prakash Shyam, Eshwaran Kowsalya, Chelladurai Karthikeyan Balavigneswaran, Balamuthu Kadalmani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  9. Pharmaceuticals (Basel, Switzerland) · 2025
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  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Venkatesan RamyaReproductive Endocrinology and Cancer Biology Laboratory, Department of Animal Science, Bharathidasan University, Tiruchirappalli, India.
Karuppiah Prakash ShyamResearch and Development Division, V.V.D and Sons Private Limited, Thoothukudi, India.
Eshwaran KowsalyaResearch and Development Division, V.V.D and Sons Private Limited, Thoothukudi, India.
Chelladurai Karthikeyan BalavigneswaranTissue Engineering and Biomaterials Laboratory, Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.
Balamuthu KadalmaniReproductive Endocrinology and Cancer Biology Laboratory, Department of Animal Science, Bharathidasan University, Tiruchirappalli, India.
Bharathidasan University · INHLL Lifecare (India) · INIndian Institute of Technology Madras · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been reported that coconut oil supplementation can reduce neuroinflammation. However, coconut oils are available as virgin coconut oil (VCO), crude coconut oil (ECO), and refined coconut oil (RCO). The impact of coconut oil extraction process (and its major fatty acid component lauric acid) at cellular antioxidant level, redox homeostasis and inflammation in neural cells is hitherto unexplained. Herein, we have shown the antioxidant levels and cellular effect of coconut oil extracted by various processes in human neuroblastoma cells (SH-SY5Y) cultured

Indexed as

antioxidantscellular redox homeostasiscoconut oil (CO)extraction processlauric acid (LA)neuroinflammationreactive oxygen species

Identifiers

PMID35360165
PMCPMC8963114
OpenAlexW4220771820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.