SynthesisFrontiers in neuroscience2022
Prognostic Role of the Neutrophil-to-Lymphocyte Ratio in Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Neutrophil-to-lymphocyte ratio, white blood cell, and C-reactive protein predicts poor outcome and increased mortality in intracerebral hemorrhage patients: a meta-analysis.Frontiers in neurology · 2023Pooled it
- High neutrophil-to-albumin ratio signals severe prognosis in LVO stroke-data from an EICU cohort.Frontiers in medicine · 2026Article
- The prognostic value of systemic inflammatory indices in elderly patients with spontaneous intracerebral hemorrhage.PloS one · 2026Observational
- Interleukin-1 regulates myeloid cell trafficking and cerebral blood flow following intracerebral haemorrhage.Disease models & mechanisms · 2025Article
- Differential Risk Factors for Hematoma Expansion in Deep and Lobar Intracerebral Hemorrhage.Neurocritical care · 2025Article
- Association between neutrophil-to-lymphocyte ratio and hematoma expansion in spontaneous intracerebral hemorrhage: A systematic review and meta-analysis.World journal of critical care medicine · 2025Article
- Clinical value of inflammatory indices in predicting poor prognosis and post-hemorrhagic hydrocephalus in patients with intraventricular hemorrhage.BMC neurology · 2025Article
- Neutrophils in Intracerebral Hemorrhage: Roles, Mechanisms, and Therapeutic Implications.Mediators of inflammation · 2025Review
- Risk factors and model construction for early neurological deterioration in patients with intracerebral hemorrhage.Frontiers in neurology · 2025Article
- Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker for Hospital-Acquired Infections in Neurosurgical Patients.Journal of inflammation research · 2025Article
- Immune Cells and Intracerebral Hemorrhage: A Causal Investigation Through Mendelian Randomization.Brain and behavior · 2025Article
- Microglial Mechanisms and Therapeutic Potential in Brain Injury Post-Intracerebral Hemorrhage.Journal of inflammation research · 2025Review
- Association of inflammatory burden index with prognosis as well as stroke-associated pneumonia in non-surgical patients with spontaneous intracerebral hemorrhage.Frontiers in neurology · 2025Article
- Systemic inflammation-based hematological indices and 90-day functional outcomes after intravenous thrombolysis in acute ischemic stroke: a systematic review.Frontiers in neurology · 2025Review
- A nomogram based on systemic inflammation response index and clinical risk factors for prediction of short-term prognosis of very elderly patients with hypertensive intracerebral hemorrhage.Frontiers in medicine · 2025Article
- Article
- Role of Neutrophils as Therapeutic Targets in Intracerebral Hemorrhage.Therapeutic innovation & regulatory science · 2024Review
- Inflammation and Adverse Outcomes in Patients With Acute Ischemic Stroke With and Without Chronic Kidney Disease.Journal of the American Heart Association · 2024Article
- Neutrophil-lymphocyte ratio: A simple and accurate biomarker for the prognosis of patients with intracerebral bleeding, a study of 115 cases.Surgical neurology international · 2024Review
- Preoperative prognostic nutrition index can independently predict the 6-month prognosis of elderly patients undergoing neurosurgical clipping for aneurysmal subarachnoid hemorrhage.Neurosurgical review · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neutrophil-to-lymphocyte ratio (NLR) plays an important role in the progression of intracerebral hemorrhage (ICH). An increasing number of studies have reported that a high NLR is correlated with poor clinical outcomes among patients with ICH. Here, we conducted a systematic review and meta-analysis to evaluate the prognostic value of NLR in the setting of ICH. We performed a comprehensive search of electronic literature databases to identify all relevant studies evaluating the prognostic role of NLR in patients with ICH. Two researchers independently screened the studies and extracted relevant data. We extracted, pooled, and weighted odds ratio (OR) and 95% confidence interval (CI) values using a generic inverse-variance method, and then evaluated the heterogeneity among studies using
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.