ArticleFrontiers in neuroscience2022
Gender Differences in the Psychosocial Determinants Underlying the Onset and Maintenance of Alcohol Use Disorder.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Neuroimaging of the effects of drug exposure or self-administration in rodents: A systematic review.Neuroscience and biobehavioral reviews · 2024Pooled it
- Gender differences in changes in alcohol consumption achieved by free provision of non-alcoholic beverages: a secondary analysis of a randomized controlled trial.BMC public health · 2024Trial
- Social Mistreatment Effect on Alcohol Misuse Trajectories Is Moderated by Subcortical Network Activation During Error Processing.Addiction biology · 2026Article
- Gender Differences in Health Risk Factors for Co-Use of Gabapentin and Opioids among Black Americans.Addiction research & theory · 2026Article
- Gender differences in a causal model of risk factors underlying early alcohol sipping.Child and adolescent psychiatry and mental health · 2026Article
- Associations Among Stressful Events, Social Support, and Alcohol Use in Women and Men.Behavioral sciences (Basel, Switzerland) · 2026Article
- [Impact of gender roles on alcohol dependence].Der Nervenarzt · 2026Review
- Addressing Substance Use Disorders Among System-Involved Girls.Child and adolescent psychiatric clinics of North America · 2026Review
- Using explainable machine learning to elucidate social and neurobehavioral risk factors linked to nonmedicinal opioid use in young adults.Scientific reports · 2025Article
- Sex-Specific Genetic Architecture and Comorbidities of Alcohol Use Behaviors.medRxiv : the preprint server for health sciences · 2025Article
- Environmental, Health, and Psychological Factors Predict Alcohol Sipping in Childhood: A Machine Learning Analysis of the ABCD Study.JAACAP open · 2025Article
- The effects of marital status, partner drinking, and sex differences on the likelihood of remission from alcohol use disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Article
- Sex/gender differences in orbitofrontal cortex reactivity underlying the associations between stress, social relationships, and problematic alcohol use.Psychological medicine · 2025Article
- Prevalence and gender-specific correlates of hazardous and binge drinking among Swedish and Finnish older adults.Alcohol, clinical & experimental research · 2025Article
- Psychiatric Morbidity Among Youth Patients at Nakuru County Referral and Teaching Hospital in Kenya: A Cross-Sectional Study.Europe's journal of psychology · 2025Article
- Integrating causal discovery and clinically-relevant insights to explore directional relationships between autistic features, sex at birth, and cognitive abilities.Psychological medicine · 2025Article
- Effects of core self-evaluation on tobacco and alcohol use among left-behind children: mediating role of fear of missing out and moderating role of parental migration category and gender.BMC psychology · 2025Article
- The link between early-life adversity and later alcohol use disorder: A role for microglia?Neurobiology of stress · 2025Article
- A narrative review on alcohol use in women: insight into the telescoping hypothesis from a biopsychosocial perspective.The American journal of drug and alcohol abuse · 2025Review
- Patterns and Challenges in Help-Seeking for Addiction among Men: A Systematic Review.Journal of clinical medicine · 2024Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
A large number of different mechanisms have been linked to Alcohol Use Disorder (AUD), including psychosocial, neurocognitive, affective, and neurobiological factors. Gender has been shown to impact the presentation and progression of AUD; yet, little work has been done to parse the different mechanisms underlying AUD within the lens of gender differences. A review of the literature on adolescence revealed that psychosocial factors, in particular lack of family social support and interactions with peers, drive the onset of alcohol use more strongly in girls relative to boys. However, research done on gender differences in disease progression in adults remains limited. Our gender-specific analysis of the mechanisms underlying AUD in adults revealed that lack of social support was causally linked to negative affect, mental health symptoms, and AUD symptom severity in women, but not men. These novel results suggest that psychosocial factors may play a gender-specific role not only in the onset of use in adolescence, but also in the maintenance of addiction in adults. If confirmed, this suggests the need for investigating gender-specific recovery trajectories. In this perspective piece, we review the literature regarding gender differences in the onset and maintenance of AUD and present original data that support unique risk factors in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.