Evidence map›Paper›PMID 35360145›Full record

ArticleGlobal pediatric health2022

Variation in Child Serum Cholesterol and Prevalence of Familiar Hypercholesterolemia: The Health Oriented Pedagogical Project (HOPP).

Ester Fabiani, Martin Frank Strand, Morten Lindberg, Nandu Goswami, Per Morten Fredriksen

Open access · goldAbstract read
In one paragraph

Article in Global pediatric health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Ester FabianiUniversity Medical Centre Ljubljana, Slovenia.
Martin Frank StrandKristiania University College, Oslo, Norway.
Morten LindbergVestfold Hospital Trust, Tonsberg, Vestfold, Norway.
Nandu GoswamiMedical University of Graz, Graz, Steiermark, Austria.
Per Morten FredriksenKristiania University College, Oslo, Norway.ORCID https://orcid.org/0000-0001-7450-2925
Høyskolen Kristiania · NOAlma Mater Europaea · SIMedical University of Graz · ATSykehuset i Vestfold · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early stages of atherosclerosis may develop in childhood due to hyperlipidemia. The aims are to investigate the prevalence of familiar hypercholesterolemia in 6 to 12-year-old children and to study the deviation in cholesterol measures. Anthropometric data and venous blood were collected from children participating in the Health Oriented Pedagogical Project (HOPP). Out of 18 children with TC > 6.0 mmol/L, 15 were tested genetically and none diagnosed with FH. The prevalence of TC > 6.0 mmol/L declined from 1.3% in 2015 to 0.5% in 2016. The mean TC was 4.30 mmol/L both years, which is lower than in earlier studies. Usage of a single TC measurement and a threshold of TC > 6.0 mmol/L in screening children for FH, may not be a good screening strategy. While lipid values have a good reliability across 2 measurements, there are variations in individual TC levels across 1 year.

Indexed as

childrencholesterolfamiliar hypercholesterolemiahyperlipidemiaprevalence

Identifiers

PMID35360145
PMCPMC8961391
OpenAlexW4220995014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.