Evidence map›Paper›PMID 35360104›Full record

ReviewFrontiers in cellular and infection microbiology2022

Gut Virome: Role and Distribution in Health and Gastrointestinal Diseases.

Laurie Spencer, Babatunde Olawuni, Pallavi Singh

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Beyond bacteria: a multi-omics view of the gut-brain axis in Parkinson's disease.Frontiers in cellular and infection microbiology · 2026
    Pooled it
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  13. Does Phage Therapy Need a Pan-Phage?Pathogens (Basel, Switzerland) · 2024
    Review
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  16. Article
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  19. The Diversity of Bacteriophages in the Human Gut.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laurie SpencerDepartment of Biological Sciences, Northern Illinois University, DeKalb, IL, United States.
Babatunde OlawuniDepartment of Biological Sciences, Northern Illinois University, DeKalb, IL, United States.
Pallavi SinghDepartment of Biological Sciences, Northern Illinois University, DeKalb, IL, United States.
Northern Illinois University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of the intestinal microbiome is an evolving field of research that includes comprehensive analysis of the vast array of microbes - bacterial, archaeal, fungal, and viral. Various gastrointestinal (GI) diseases, such as Crohn's disease and ulcerative colitis, have been associated with instability of the gut microbiota. Many studies have focused on importance of bacterial communities with relation to health and disease in humans. The role of viruses, specifically bacteriophages, have recently begin to emerge and have profound impact on the host. Here, we comprehensively review the importance of viruses in GI diseases and summarize their influence in the complex intestinal environment, including their biochemical and genetic activities. We also discuss the distribution of the gut virome as it relates with treatment and immunological advantages. In conclusion, we suggest the need for further studies on this critical component of the intestinal microbiome to decipher the role of the gut virome in human health and disease.

Indexed as

BacteriophagesGastrointestinal DiseasesGastrointestinal MicrobiomeVirusesHumansViromebacteriophageeukaryotic virusgastro-intestinal diseasephage therapyvirome

Identifiers

PMID35360104
PMCPMC8960297
OpenAlexW4221094197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.