Evidence map›Paper›PMID 35360076›Full record

ArticleFrontiers in endocrinology2022

Associations Between Abdominal Obesity Indices and Nonalcoholic Fatty Liver Disease: Chinese Visceral Adiposity Index.

Xueyu Chen, Fengxue Shi, Juan Xiao, Fengyan Huang, Fang Cheng, Lihua Wang, Yanli Ju, Yong Zhou, Hongying Jia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  9. [Predictive value of a Chinese visceral adiposity index for metabolic associated fatty liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xueyu ChenDepartment of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Fengxue ShiDepartment of Clinical Skills Center, School of Clinical Medicine, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Juan XiaoCenter of Evidence-Based Medicine, Institute of Medical Sciences, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Fengyan HuangDepartment of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Fang ChengDepartment of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Lihua WangDepartment of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yanli JuDepartment of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yong ZhouClinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hongying JiaDepartment of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Shandong University · CNSecond Hospital of Shandong University · CNShandong First Medical University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver metabolic disease worldwide. Up to 70%-80% of patients with NAFLD were obese, especially abdominal obesity. Many indicators of abdominal obesity have been reported, including waist circumference (WC), visceral obesity index (VAI), lipid accumulation (LAP), and Chinese VAI (CVAI). However, few studies investigated the associations between these indices with NAFLD. This present study aims to explore the associations between abdominal obesity indices with NAFLD. A total of 7,238 participants were involved in the cross-sectional study, and 1,584 participants were included in the longitudinal study from Jidong communities. NAFLD was assessed by abdominal ultrasonography. The trajectory of WC, VAI, LAP, and CVAI during 2013-2016 was identified by a group-based trajectory model. The logistic regression and Cox proportional hazards models analyzed the correlations and causality between abdominal obesity indices with NAFLD. In this study, the prevalence and incidence of NAFLD are approximately 44% and 26%, respectively. In the cross-sectional study, WC, VAI, LAP, and CVAI are associated with NAFLD. After adjustment for potential confounders, the moderate-rising and high-rising groups of CVAI had the highest risk of NAFLD in longitudinal analysis (hazard ratio (HR): 3.903, 95%CI: 2.434-6.259; HR: 5.694 95%CI: 3.098-10.464, respectively). Receiving operating characteristic curves show that CVAI has the best diagnostic value for NAFLD (area under the curve (AUC) = 0.868). CVAI is independently associated with the risk of NAFLD and may also have an important value to the diagnosis of NAFLD.

Indexed as

Non-alcoholic Fatty Liver DiseaseAdiposityChinaCross-Sectional StudiesHumansLongitudinal StudiesObesityObesity, Abdominalabdominal obesityabdominal obesity indicesCVAINAFLDvisceral adiposity

Identifiers

PMID35360076
PMCPMC8960385
OpenAlexW4220858927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.