Evidence map›Paper›PMID 35359978›Full record

ArticleFrontiers in immunology2022

Type I Interferon-Induced TMEM106A Blocks Attachment of EV-A71 Virus by Interacting With the Membrane Protein SCARB2.

Xuemin Guo, Shinuan Zeng, Xiaoxin Ji, Xiaobin Meng, Nanfeng Lei, Hai Yang, Xin Mu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Current status of hand-foot-and-mouth disease.Journal of biomedical science · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xuemin GuoMeizhou People's Hospital, Meizhou, China.
Shinuan ZengDepartment of Surgery, HKU-SZH & Faculty of Medicine,The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Xiaoxin JiSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Xiaobin MengMeizhou People's Hospital, Meizhou, China.
Nanfeng LeiMeizhou People's Hospital, Meizhou, China.
Hai YangMeizhou People's Hospital, Meizhou, China.
Xin MuSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Meizhou City People's Hospital · CNTianjin University · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterovirus A71 (EV-A71) and Coxsackievirus A16 (CV-A16) are the main causative agents of hand, foot and mouth disease (HFMD) worldwide. Studies showed that EV-A71 and CV-A16 antagonize the interferon (IFN) signaling pathway; however, how IFN controls this viral infection is largely unknown. Here, we identified an IFN-stimulated gene,

Indexed as

EnterovirusEnterovirus A, HumanEnterovirus InfectionsHand, Foot and Mouth DiseaseInterferon Type IAntigens, ViralDNA VirusesHumansLysosomal Membrane ProteinsMembrane ProteinsReceptors, ScavengerAntigens, ViralInterferon Type ILysosomal Membrane ProteinsMembrane ProteinsReceptors, ScavengerSCARB2 protein, humanantiviral activityenterovirus A71interferon-stimulated geneSCARB2TMEM106A

Identifiers

PMID35359978
PMCPMC8963425
OpenAlexW4220812652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.