Evidence map›Paper›PMID 35359974›Full record

ArticleFrontiers in immunology2022

Prevalence, Abundance, and Virulence of Adherent-Invasive

Mireia López-Siles, Carla Camprubí-Font, Eva M Gómez Del Pulgar, Miriam Sabat Mir, David Busquets, Yolanda Sanz, Margarita Martinez-Medina

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Adherent-InvasiveMicroorganisms · 2026
    Article
  3. Deciphering the Implications ofPathogens (Basel, Switzerland) · 2026
    Review
  4. Expansion resistance against genotoxicFrontiers in microbiology · 2026
    Article
  5. Article
  6. TheGut microbes · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Colonizing and Virulence Factors in Enterotoxigenic Escherichia coli from Peru.The American journal of tropical medicine and hygiene · 2023
    Article
  18. Article
  19. Review
  20. Role of adherent invasiveWorld journal of clinical cases · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mireia López-SilesMicrobiology of Intestinal Diseases, Biology Department, Universitat de Girona, Girona, Spain.
Carla Camprubí-FontMicrobiology of Intestinal Diseases, Biology Department, Universitat de Girona, Girona, Spain.
Eva M Gómez Del PulgarInstituto de Agroquímica y Tecnología de Alimentos, Spanish National Research Council (CSIC), Paterna, Spain.
Miriam Sabat MirDepartment of Gastroenterology, Hospital Santa Caterina, Salt, Spain.
David BusquetsDepartment of Gastroenterology, Hospital Universitari Doctor Josep Trueta, Girona, Spain.
Yolanda SanzInstituto de Agroquímica y Tecnología de Alimentos, Spanish National Research Council (CSIC), Paterna, Spain.
Margarita Martinez-MedinaMicrobiology of Intestinal Diseases, Biology Department, Universitat de Girona, Girona, Spain.
University of Girona · ESConsejo Superior de Investigaciones Científicas · ESHospital Santa Caterina · ESHospital Universitari de Girona Doctor Josep Trueta · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & Aims: Adherent-invasive Methods: The AIEC phenotype was investigated in 4,233 Results: In UC, AIEC prevalence was intermediate between CD and H subjects (UC: 35.7%, CD: 55.0%, H: 21.4%), and similar to CD patients with colonic disease (C-CD: 40.0%). In CRC, the prevalence was lower (6.7%) than these groups. In patients with AIEC, the estimated abundance was similar across all intestinal conditions. All AIEC strains isolated from UC and CRC belonged to the B1 phylogroup, except for a strain of the A phylogroup, and the majority (75% of clonally distinct AIEC) harbored the Afa/Dr operon and the Conclusion: We support the hypothesis that AIEC-like strains can be involved not only in CD but also in UC. Further works are needed to study the virulence particularities of these groups of strains and to determine if there is a causative link between AIEC and UC. In contrast, we rule out the possible association of AIEC with CRC. In addition, to further study the

Indexed as

Celiac DiseaseColitis, UlcerativeColorectal NeoplasmsCrohn DiseaseEscherichia coli InfectionsBacterial AdhesionChildEscherichia coliHumansPhylogenyPrevalenceVirulenceadherent-invasive Escherichia colicoeliac diseasecolorectal cancerCrohn’s diseaseulcerative colitis

Identifiers

PMID35359974
PMCPMC8960851
OpenAlexW4220692354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.