ReviewFrontiers in immunology2022
Mind the "Vaccine Fatigue".
Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 84 citations in OpenAlex.
- RSV vaccine uptake among Medicare Advantage enrollees: August 2023 to December 2024.Human vaccines & immunotherapeutics · 2026Article
- Associations of herpes zoster disease perceptions, altruism and family harmony with herpes zoster vaccination uptake among older adults in Shenzhen, China.Human vaccines & immunotherapeutics · 2026Article
- Dynamic trends and determinants of COVID-19 vaccine hesitancy among adults in China during 2021-2022: A multilevel analysis based on four national cross-sectional surveys.Human vaccines & immunotherapeutics · 2026Article
- Integrating Pharmacists Into Aged Care Vaccination: Strengthening Public Health Immunisation Systems Through the Aged Care on-Site Pharmacist Program (ACOP) in Australia.Australasian journal on ageing · 2026Article
- Factors associated with severe COVID-19 in immunocompromised subgroups in England from 2020 to 2024: an OpenSAFELY cohort study.EBioMedicine · 2026Article
- Article
- Low effectiveness of influenza vaccines vis-à-vis mechanism of protection by vaccines - potential causes and recommendations to improve control of influenza.Frontiers in immunology · 2026Review
- Pandemic fatigue and associated factors: a meta-analysis using the COM-B model.Frontiers in psychology · 2026Review
- Uptake, willingness, and practices toward seasonal influenza vaccination among healthcare workers in China: a cross-sectional study.Frontiers in public health · 2026Article
- Bridging the knowledge gap: Thai parents' perspectives on dengue infection and its vaccination and the need for targeted promotion.PLoS neglected tropical diseases · 2026Article
- Respiratory virus genomic epidemiology during post-pandemic re-emergence of influenza in Australia.Virus evolution · 2026Article
- Understanding COVID-19 vaccine hesitancy among older adults in post-zero-COVID China: a predictive modeling study.BMC geriatrics · 2025Article
- Changing pace of human papillomavirus vaccination among U.S. adolescents and young adults: the National Health and Nutrition Examination Survey, 2007-August 2023.Cancer causes & control : CCC · 2025Article
- Understanding the drivers and barriers of elderly vaccination in post-pandemic China: a qualitative study in Shenzhen.BMC public health · 2025Article
- Disparities in Seasonal Influenza Vaccination in Europe.Immunity, inflammation and disease · 2025Review
- COVID-19 and Influenza Vaccine Uptake Among Nurses and Children Living in Their Households: A Cross-Sectional Study.Health science reports · 2025Article
- Preparation of Monoclonal Antibodies Against the gD Protein of Feline Herpesvirus Type-1 by mRNA Immunization.Veterinary sciences · 2025Article
- Can ChatGPT Counter Vaccine Hesitancy? An Evaluation of ChatGPT's Responses to Simulated Queries from the General Public.Healthcare (Basel, Switzerland) · 2025Article
- Vaccination burnout impedes the compliance with multiple-dose administration of vaccines.Scientific reports · 2025Article
- Stakeholder perspective and sentiment in a rapidly growing United States adult vaccination environment.iScience · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 5 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Omicron scares and speculations are gaining momentum. Amid the nonstop debates and discussions about COVID-19 vaccines, the "vaccine fatigue" phenomenon may become more prevalent. However, to date, no research has systematically examined factors that shape people's vaccine fatigue. To bridge the research gap, this study aims to investigate the antecedents that cause or catalyze people's vaccine fatigue. Methods: A narrative literature review was conducted in PubMed, Scopus, and PsycINFO to identify factors that shape people's vaccine fatigue. The search was completed on December 6, 2021, with a focus on scholarly literature published in English. Results: A total of 37 articles were reviewed and analyzed. Vaccine fatigue was most frequently discussed in the context of infectious diseases in general at the pre-vaccination stage. Vaccine fatigue has been identified in the general public, the parents, and the doctors. Overall, a wide range of antecedents to vaccine fatigue has been identified, ranging from the frequency of immunization demands, vaccine side effects, misconceptions about the severity of the diseases and the need for vaccination, to lack of trust in the government and the media. Conclusion: Vaccine fatigue is people's inertia or inaction towards vaccine information or instruction due to perceived burden and burnout. Our study found that while some contributors to vaccine fatigue are rooted in limitations of vaccine sciences and therefore can hardly be avoided, effective and empathetic vaccine communications hold great promise in eliminating preventable vaccine fatigue across sectors in society.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.