Evidence map›Paper›PMID 35359855›Full record

ArticleFrontiers in pharmacology2022

Design and Characterization of Paclitaxel-Loaded Polymeric Nanoparticles Decorated With Trastuzumab for the Effective Treatment of Breast Cancer.

Mirina Sakhi, Abad Khan, Zafar Iqbal, Ismail Khan, Abida Raza, Asmat Ullah, Fazli Nasir, Saeed Ahmad Khan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Mirina SakhiDepartment of Pharmacy, University of Swabi, Swabi, Pakistan.
Abad KhanDepartment of Pharmacy, University of Swabi, Swabi, Pakistan.
Zafar IqbalDepartment of Pharmacy, University of Peshawar, Peshawar, Pakistan.
Ismail KhanDepartment of Pharmacy, University of Swabi, Swabi, Pakistan.
Abida RazaNational Institute of LASER and Optronics, Nilore, Pakistan.
Asmat UllahDepartment of Pharmacy, University of Swabi, Swabi, Pakistan.
Fazli NasirDepartment of Pharmacy, University of Peshawar, Peshawar, Pakistan.
Saeed Ahmad KhanDepartment of Pharmacy, Kohat University of Science and Technology, Kohat, Pakistan.
University of Swabi · PKUniversity of Peshawar · PKKohat University of Science and Technology · PKPakistan Institute of Nuclear Science and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to design and formulate an antibody-mediated targeted, biodegradable polymeric drug delivery system releasing drug in a controlled manner to achieve a therapeutic goal for the effective treatment of breast cancer. Antibody-mediated paclitaxel-loaded PLGA polymeric nanoformulations were prepared by the solvent evaporation method using different experimental parameters and compatibility studies. The optimized formulations were selected for

Indexed as

biodegradablebreast cancercytotoxicitydrug-deliverypaclitaxelPLGApolymerictrastuzumab

Identifiers

PMID35359855
PMCPMC8964068
OpenAlexW4220698333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.