Evidence map›Paper›PMID 35359838›Full record

ReviewFrontiers in pharmacology2022

Traditional Knowledge to Contemporary Medication in the Treatment of Infectious Disease Dengue: A Review.

Mamta Dhiman, Lakshika Sharma, Abhishek Dadhich, Poonam Dhawan, M M Sharma

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mamta DhimanDepartment of Biosciences, Manipal University Jaipur, Jaipur, India.
Lakshika SharmaDepartment of Biosciences, Manipal University Jaipur, Jaipur, India.
Abhishek DadhichDepartment of Biosciences, Manipal University Jaipur, Jaipur, India.
Poonam DhawanSchool of Science, Nirwan University, Jaipur, India.
M M SharmaDepartment of Biosciences, Manipal University Jaipur, Jaipur, India.
Manipal University JaipurJaipur National University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue has become a worldwide affliction despite incessant efforts to search for a cure for this long-lived disease. Optimistic consequences for dengue vaccine are implausible as the efficiency is tied to previous dengue virus (DENV) exposure and a very high cost is required for large-scale production of vaccine. Medicinal plants are idyllic substitutes to fight DENV infection since they constitute important components of traditional medicine and show antiviral properties, although the mechanism behind the action of bioactive compounds to obstruct viral replication is less explored and yet to be discovered. This review includes the existing traditional knowledge on how DENV infects and multiplies in the host cells, conscripting different medicinal plants that obtained bioactive compounds with anti-dengue properties, and the probable mechanism on how bioactive compounds modulate the host immune system during DENV infection. Moreover, different plant species having such bioactive compounds reported for anti-DENV efficiency should be validated scientifically

Indexed as

bioactive compounddengueimmunomodulatory responseplant medicamentstraditional medicine

Identifiers

PMID35359838
PMCPMC8963989
OpenAlexW4220990309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.