Evidence map›Paper›PMID 35359658›Full record

ArticleFrontiers in neurology2022

Impact of Voluntary Muscle Activation on Stretch Reflex Excitability in Individuals With Hemiparetic Stroke.

Jacqueline R Patterson, Julius P A Dewald, Justin M Drogos, Netta Gurari

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jacqueline R PattersonDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.
Julius P A DewaldDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.
Justin M DrogosDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.
Netta GurariDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.
Northwestern University · US

Funding

EFFECT OF NEURAL CONSTRAINTS ON MOVEMENT IN STROKER01HD039343 · NICHD · REHABILITATION INSTITUTE OF CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2000 to 2026
$6.0M
Contralesional Corticobulbospinal Structural and Functional Changes Post Stroke: Biomarkers for the upper limb flexion synergyR01NS105759 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P · 2019 to 2023
$2.7M
Upper-Extremity Torque Perceptual Impairments in Chronic Hemiparetic StrokeK25HD096116 · NICHD · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GURARI, NETTA · 2018 to 2022
$696k
Determination of the Recruitment of Indirect Motor Pathways in Chronic Hemiparetic StrokeR21HD099710 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P, YANG, YUAN · 2019 to 2020
$416k
NICHD NIH HHS K25 HD096116NICHD NIH HHS R21 HD099710NINDS NIH HHS R01 NS105759
6 · The paper itself

Abstract

Objective: To characterize how, following a stretch-induced attenuation, volitional muscle activation impacts stretch reflex activity in individuals with stroke. Methods: A robotic device rotated the paretic elbow of individuals with hemiparetic stroke from 70° to 150°, and then back to 70° elbow flexion at an angular speed of 120°/s. This stretching sequence was repeated 20 times. Subsequently, participants volitionally activated their elbow musculature or rested. Finally, the stretching sequence was repeated another 20 times. The flexors' stretch reflex activity was quantified as the net torque measured at 135°. Results: Data from 15 participants indicated that the stretching sequence attenuated the flexion torque ( Conclusions: Stretch reflex attenuation induced by repeated fast stretches may be nullified when individuals post-stroke volitionally activate their muscles. In contrast, resting may enable a sustained reflex attenuation if the individual remains relaxed. Significance: Stretching is commonly implemented to reduce hyperactive stretch reflexes following a stroke. These findings suggest that stretch reflex accommodation arising from repeated fast stretching may be reversed once an individual volitionally moves their paretic arm.

Indexed as

hypertoniamotoneuronroboticsspasticitystretchingstretch reflexstroke

Identifiers

PMID35359658
PMCPMC8964046
OpenAlexW4220957401

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.