Evidence map›Paper›PMID 35359607›Full record

ArticleFrontiers in molecular biosciences2022

Isolated Components From Spider Venom Targeting Human Glioblastoma Cells and Its Potential Combined Therapy With Rapamycin.

Marcus Caballero, Natalia Barreto, Amanda Pires Bonfanti, Jaqueline Munhoz, Thomaz Rocha E Silva, Rafael Sutti, Liana Verinaud, Felipe Cezar Pinheiro de Mato, Guilherme Pauperio Lanfredi, Catarina Rapôso

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Marcus CaballeroFaculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
Natalia BarretoFaculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
Amanda Pires BonfantiFaculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
Jaqueline MunhozFaculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
Thomaz Rocha E SilvaFaculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, Brazil.
Rafael SuttiFaculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, Brazil.
Liana VerinaudDepartamento de Biologia Estrutural e Funcional, Instituto de Biologia, UNICAMP, Campinas, Brazil.
Felipe Cezar Pinheiro de MatoFaculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
Guilherme Pauperio LanfrediDepartamento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), São Paulo, Brazil.
Catarina RapôsoFaculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRFaculdade de Ciências Médicas da Santa Casa de São Paulo · BRHospital Israelita Albert Einstein · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastomas (GBs) are responsible for a higher mortality rate among gliomas, corresponding to more than 50% of them and representing a challenge in terms of therapy and prognosis. Peptide-based antineoplastic therapy is a vast and promising field, and these molecules are one of the main classes present in spider venoms. Recently, our research group demonstrated the cytotoxic effects of

Indexed as

animal venomcancer therapycytotoxicityglioblastomamTORrapamycin

Identifiers

PMID35359607
PMCPMC8964069
OpenAlexW4220994665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.