Evidence map›Paper›PMID 35359602›Full record

ArticleFrontiers in molecular biosciences2022

Ni

Ewa Izabela Podobas, Danuta Gutowska-Owsiak, Sébastien Moretti, Jarosław Poznański, Mariusz Kulińczak, Marcin Grynberg, Aleksandra Gruca, Arkadiusz Bonna, Dawid Płonka, Tomasz Frączyk and 2 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Revisiting the Roles of Filaggrin in Atopic Dermatitis.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Ewa Izabela PodobasInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Danuta Gutowska-OwsiakMedical Research Council Human Immunology Unit, National Institute for Health Research Oxford Biomedical Research Centre, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Sébastien MorettiSIB Swiss Institute of Bioinformatics, Vital-IT Team, Lausanne, Switzerland.
Jarosław PoznańskiInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Mariusz KulińczakThe Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Marcin GrynbergInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Aleksandra GrucaInstitute of Informatics, Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, Gliwice, Poland.
Arkadiusz BonnaDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Dawid PłonkaInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Tomasz FrączykInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Graham OggMedical Research Council Human Immunology Unit, National Institute for Health Research Oxford Biomedical Research Centre, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Wojciech BalInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Institute of Biochemistry and Biophysics, Polish Academy of Sciences · PLMedical Research Council · GBNational Institute for Health Research · GBSIB Swiss Institute of Bioinformatics · CHSilesian University of Technology · PLThe Maria Sklodowska-Curie National Research Institute of Oncology · PLUniversity of Cambridge · GBUniversity of Warsaw · PL

Funding

Medical Research Council MC_UU_00008/5
6 · The paper itself

Abstract

Deficiency in a principal epidermal barrier protein, filaggrin (FLG), is associated with multiple allergic manifestations, including atopic dermatitis and contact allergy to nickel. Toxicity caused by dermal and respiratory exposures of the general population to nickel-containing objects and particles is a deleterious side effect of modern technologies. Its molecular mechanism may include the peptide bond hydrolysis in X

Indexed as

filaggrinhuman proteomeNi2+-assisted hydrolysisnickel allergynickel toxicityprotein degradation

Identifiers

PMID35359602
PMCPMC8960189
OpenAlexW4220988153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.