ArticleAnnals of Indian Academy of Neurology
Neurological Facets of Scrub Typhus: A Comprehensive Narrative Review.
Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Movement Disorders in Scrub Typhus: A Systematic Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Pooled it
- Scrub typhus-associated movement and gait disorders: A systematic review with principal component analysis and in silico mechanistic modelling.Tropical medicine & international health : TM & IH · 2025Pooled it
- Neurological manifestations of scrub typhus infection: A systematic review and meta-analysis of clinical features and case fatality.PLoS neglected tropical diseases · 2022Pooled it
- A humanized IFN-γ mouse model reveals skin eschar formation, enhanced susceptibility and scrub typhus pathogenesis.PLoS pathogens · 2026Article
- Bilateral thalamic involvement in scrub typhus meningoencephalitis: a case report of an uncommon neuroimaging pattern mimicking Japanese encephalitis.BMJ neurology open · 2026Article
- Construction and validation of a predictive model for meningoencephalitis in pediatric scrub typhus based on machine learning algorithms.Emerging microbes & infections · 2025Article
- Challenging Neurological Presentation: Scrub Typhus with Meningoencephalitis and Multiple Cranial Nerve Involvement.Neurology and clinical neuroscience · 2024Article
- Diagnostic markers of acute encephalitis syndrome and COVID-associated multisystem inflammatory syndrome in children from Southern India.Journal of medical virology · 2024Article
- Guillain-Barre syndrome following scrub typhus: a case report and literature review.BMC neurology · 2024Review
- Overview of management of infection-related movement disorders with focus on specific-infections.Clinical parkinsonism & related disorders · 2024Article
- Case Report: Encephalitis with Initial Manifestation of Orientia Tsutsugamushi Infection Detected by Metagenomic Next-Generation Sequencing.Infection and drug resistance · 2024Article
- A case of acute encephalitis syndrome and cranial nerve palsy secondary to scrub typhus: A rare presentation from Western Nepal.Clinical case reports · 2023Article
- Association of Scrub Typhus in Children with Acute Encephalitis Syndrome and Meningoencephalitis, Southern India.Emerging infectious diseases · 2023Review
- Neurological manifestations of scrub typhus: encephalitis and Guillain-Barré syndrome (GBS).BMJ case reports · 2023Article
- Brain transcriptomics reveal the activation of neuroinflammation pathways during acuteFrontiers in immunology · 2023Article
- Case Report: Optic neuritis as the initial presentation of Orientia tsutsugamushi infection detected by metagenomic next-generation sequencing.Frontiers in immunology · 2023Article
- Scrub typhus with opsoclonus-myoclonus-ataxia-seizure as primary presentations.Journal of neurosciences in rural practiceArticle
- Scrub Typhus for the Neurologist: Forget Me Not.Annals of Indian Academy of NeurologyArticle
- A Case Series of Scrub Meningoencephalitis from a Tertiary Care Center in North India.Annals of Indian Academy of NeurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scrub typhus is one of the most frequent causes of acute febrile illness in South and South-east Asian countries. Neurological features accompany 20% of scrub typhus infections, and may affect the central or peripheral nervous system, and sometime, may even occur in combination. Of late, its recognition among clinicians has increased with widening detection of its cutaneous hallmark, called eschar. Multiple mechanisms underlie neurological involvement, including direct invasion (meningitis, encephalitis), vasculitis (myositis) or immune-mediated mechanisms (opsoclonus, myoclonus, optic neuritis, Guillain-Barre syndrome). Despite an immunological basis for several neurological manifestations, response to doxycycline is remarkable, although immune therapy may be necessary for severe involvement. Scientific literature on scrub typhus neurology chiefly emanates from case reports, case series and small studies, and a comprehensive review is warranted to aid clinicians in recognising neurological involvement. This review aims at enriching this gap, and summarises clinical features, laboratory findings, and treatment options for various neurological facets of scrub typhus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.