Evidence map›Paper›PMID 35359461›Full record

ReviewJournal of the renin-angiotensin-aldosterone system : JRAAS2022

Cardiorenal Disease in COVID-19 Patients.

Muhtasham Sifaat, Pinak Patel, Razan Sheikh, Dawood Ghaffar, Hitesh Vaishnav, Ludmila Nahar, Sonia Rupani, Syed Quadri

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of the renin-angiotensin-aldosterone system : JRAAS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Muhtasham SifaatDeBusk College of Osteopathic Medicine, Lincoln Memorial University, 9737 Cogdill Rd, Knoxville, TN 37932, USA.
Pinak PatelDeBusk College of Osteopathic Medicine, Lincoln Memorial University, 9737 Cogdill Rd, Knoxville, TN 37932, USA.
Razan SheikhDeBusk College of Osteopathic Medicine, Lincoln Memorial University, 9737 Cogdill Rd, Knoxville, TN 37932, USA.
Dawood GhaffarDeBusk College of Osteopathic Medicine, Lincoln Memorial University, 9737 Cogdill Rd, Knoxville, TN 37932, USA.
Hitesh VaishnavDeBusk College of Osteopathic Medicine, Lincoln Memorial University, 9737 Cogdill Rd, Knoxville, TN 37932, USA.
Ludmila NaharDepartment of Medicine, School of Medicine/John D. Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Sonia RupaniSchool of Medical Sciences, Lincoln Memorial University, 9737 Cogdill Rd, Knoxville, TN 37932, USA.
Syed QuadriDeBusk College of Osteopathic Medicine, Lincoln Memorial University, 9737 Cogdill Rd, Knoxville, TN 37932, USA.ORCID https://orcid.org/0000-0003-4921-7836
Lincoln Memorial University · USUniversity of Mississippi Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is an illness caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Mutations in the genetic coding and the variations in the spike proteins are critical for the virus's mechanism of facilitating fusion with the human host, making the disease more severe. Recent research indicates that comorbidities including diabetes, hypertension, renal disease, heart failure, and atherosclerosis play a significant role in the severity and high mortality rates of (COVID-19), suggesting that perhaps the metabolic syndrome and its components are associated with COVID-19 morbidity. Primarily, angiotensin-converting enzyme 2 (ACE2) receptor is identified as the entrance receptor of SARS-CoV-2. Increased ACE2 expression, endothelial dysfunction plays a vital role in the progression and severity of complications developed due to COVID-19. In this review, we will discuss the association and management of cardiorenal disease and COVID-19.

Indexed as

COVID-19Hypertension, RenalHumansPeptidyl-Dipeptidase ASARS-CoV-2Peptidyl-Dipeptidase A

Identifiers

PMID35359461
PMCPMC8956393
OpenAlexW4221013025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.