Evidence map›Paper›PMID 35359343›Full record

ArticleJournal of oncology2022

Survival Analysis and a Novel Nomogram Model for Progression-Free Survival in Patients with Prostate Cancer.

Yuefu Han, Xingqiao Wen, Dong Chen, Xiaojuan Li, Qu Leng, Yuehui Wen, Jun Li, Weian Zhu

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Yuefu HanDepartment of Urology, Shenzhen Hospital, The Third College of Clinical Medicine, Southern Medical University, Shenzhen, 518100 Guangdong, China.
Xingqiao WenDepartment of Urology, Shenzhen Hospital, The Third College of Clinical Medicine, Southern Medical University, Shenzhen, 518100 Guangdong, China.ORCID https://orcid.org/0000-0003-1809-9208
Dong ChenDepartment of Urology, Yuebei People's Hospital Affiliated to Medical College of Shantou University, Shaoguan, 512026 Guangdong, China.
Xiaojuan LiDepartment of Health Care, Shenzhen Hospital, The Third College of Clinical Medicine, Southern Medical University, Shenzhen, 518100 Guangdong, China.
Qu LengDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.
Yuehui WenDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515 Guangdong, China.
Jun LiDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.
Weian ZhuDepartment of Urology, Third Hospital of Sun Yat-sen University, Guangzhou, 510630 Guangdong, China.
Shantou University · CNSun Yat-sen University · CNZhujiang Hospital · CNNanfang Hospital · CNSouthern Medical University Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study sought to perform a survival analysis and construct a prognostic nomogram model based on the Gleason grade, total prostate-specific antigen (tPSA), alkaline phosphate (ALP), and TNM stage in patients with prostate cancer (PCa). Methods: The progression-free survival (PFS) of 255 PCa patients was analyzed in this study. The prognostic value of tPSA and ALP was evaluated using the Kaplan-Meier survival curves and Cox regression analysis, and a nomogram model based on the Gleason grade, tPSA, ALP, and TNM stage was further established for PFS prediction in PCa patients. Results: PCa patients with different Gleason grades, tPSA and ALP levels, and TNM stages presented distinct PFS. The Gleason grade, tPSA, ALP, and TNM stage were four independent prognostic indicators. The C-index of the established nomogram was 0.705 for PFS in the test cohort and 0.687 for the validation cohort, and the calibration curves indicated a good consistency between predicted and actual PFS in PCa patients. Conclusion: The data of this study demonstrated that the Gleason grade, tPSA, ALP, and TNM stage of PCa patients are independently correlated with PFS, and a nomogram model based on these indicators may be valuable for the PFS prediction in PCa patient.

Identifiers

PMID35359343
PMCPMC8964199
OpenAlexW4221012222

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.