ArticleInternational journal of medical informatics2022
Coordinated use of Health Level 7 standards to support clinical decision support: Case study with shared decision making and drug-drug interactions.
Article in International journal of medical informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Conceptualizing clinical decision support as complex interventions: a meta-analysis of comparative effectiveness trials.Journal of the American Medical Informatics Association : JAMIA · 2022Pooled it
- A Standards-Based, Cloud-Hosted CDS System for Gonorrhea Treatment and HIV Screening.Learning health systems · 2026Article
- Combining International Standards to Develop Clinical Decision Support for Parent Smoking Cessation in Pediatrics.Journal of medical Internet research · 2025Article
- Challenges to Reduce Alert Burden Using Current Decision Support Infrastructure in Two Commercial EHR Systems: Lessons Learned and Path Forward.Applied clinical informatics · 2025Article
- A scoping review of rule-based clinical decision support malfunctions.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Machine Learning-Enabled Clinical Information Systems Using Fast Healthcare Interoperability Resources Data Standards: Scoping Review.JMIR medical informatics · 2023Article
- Smart Contract Authentication assisted GraphMap-Based HL7 FHIR architecture for interoperable e-healthcare system.Heliyon · 2023Article
- Shared Decision-Making for Drug-Drug Interactions: Formative Evaluation of an Anticoagulant Drug Interaction.JMIR formative research · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundDespite advances in interoperability standards, it remains challenging and often costly to share clinical decision support (CDS) across healthcare organizations. This is due in part to limited coordination among CDS components. To improve coordination of CDS components, Health Level 7 (HL7) has developed a suite of interoperability standards with Fast Health Interoperability Resources (FHIR) specification as a common information model. Evidence is needed to determine the feasibility of implementing these CDS components; therefore, the objective of this study was to investigate the coordination of emerging HL7 standards with modular CDS architecture components.
methodsWe used a modular, standards-based architecture consisting of four components: data, logic, services, and applications. The implementation use-case was an application to support shared decision making in the context of drug-drug interactions (DDInteract).
resultsDDInteract uses FHIR as the data representation model, Clinical Quality Language for logic representation, CDS Hooks for the services layer, and Substitutable Medical Apps Reusable Technologies for application integration. DDInteract was first implemented in a sandbox environment and then in an electronic health record (Epic®) test environment. DDInteract can be integrated in clinical workflows through on-demand access from a menu or through CDS Hooks upon opening a patient's record or placing a medication order.
conclusionIn the context of drug interactions, DDInteract is the first application to leverage a full stack of emerging interoperability standards for each component of modular CDS architecture. The demonstrated feasibility of interoperable components can be generalized to other modular CDS applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.