Evidence map›Paper›PMID 35358251›Full record

ArticlePloS one2022

Prepregnancy BMI, gestational weight gain and offspring caries experience: Avon longitudinal study of parents and children.

Aderonke A Akinkugbe, Tegwyn H Brickhouse, Dipankar Bandyopadhyay, Marcelle M Nascimento, Gary D Slade

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Aderonke A AkinkugbeDepartment of Dental Public Health and Policy, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia, United States of America.ORCID 0000-0003-1207-9732
Tegwyn H BrickhouseDepartment of Dental Public Health and Policy, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia, United States of America.
Dipankar BandyopadhyayDepartment of Biostatistics, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, United States of America.ORCID 0000-0001-5421-1725
Marcelle M NascimentoDepartment of Restorative Dental Sciences, University of Florida College of Dentistry, Gainesville, Florida, United States of America.
Gary D SladePediatric Public Health Department, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Virginia Commonwealth University · USUniversity of Florida · USUniversity of North Carolina at Chapel Hill · US

Funding

Are prenatal smoking and pregnancy BMI risk factors for caries experience in the offspring?R03DE028403 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI AKINKUGBE, ADERONKE ARAMIDE · 2019 to 2020
$310k
Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009NIDCR NIH HHS L40 DE028120NIDCR NIH HHS R03 DE028403Wellcome Trust
6 · The paper itself

Abstract

Pre-existing maternal overweight/obesity and pregnancy weight gain are associated with adverse birth outcomes such as low birth weight and prematurity, which may increase the risk of developmental tooth defects and early childhood caries. We sought to investigate the association between prepregnancy BMI, gestational weight gain (GWG) and the risk of early childhood caries. Data from 1,429 mother-offspring participants of the 1991/1992 Avon Longitudinal Study of Parents and Children were analyzed. The exposures were prepregnancy BMI (under/normal weight vs. overweight/obese), and gestational weight gain (GWG) based on the Institute of Medicine's recommended levels. The main outcome measured was offspring caries experience determined by clinical oral examinations at three time points. Log binomial regression estimated risk ratios and 95% confidence intervals. Seventy six percent (76%) of the mothers were under/normal weight prepregnancy, 39% and 26% respectively gained less and more than the recommended weight for their prepregnancy BMI during pregnancy. Being overweight/obese prepregnancy was associated with unadjusted RR (95% CI) of offspring caries of 1.16 (0.90, 1.51) at 31-months, 1.20 (0.96, 1.49) at 43-months and 1.09 (0.91, 1.30) at 61-months. GWG less than recommended was associated with higher unadjusted offspring caries experience of 1.13 (0.86, 1.48), 1.17 (0.92, 1.48) and 1.04 (0.87, 1.25) at 31-months, 43-months and 61-months respectively. There was insufficient evidence to indicate an association between prepregnancy BMI and gestational weight gain on offspring caries experience risk.

Indexed as

Gestational Weight GainBody Mass IndexChildChild, PreschoolDental Caries SusceptibilityFemaleHumansLongitudinal StudiesMothersObesityOverweightPregnancyWeight Gain

Identifiers

PMID35358251
PMCPMC8970488
OpenAlexW4220665926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.