Evidence map›Paper›PMID 35358217›Full record

ArticlePloS one2022

Correlates of prevalent syphilis infection among men who have sex with men (MSM) living with HIV attending the HIV clinic in Trinidad.

R Jeffrey Edwards, Abigail Mohammed, Leon-Omari Lavia, Jonathan Edwards, Shiva Verma, Saketh Reddy, Gregory Boyce

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. High rates of Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis co-infection in people with HIV: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  2. Article
  3. High Prevalence of Asymptomatic STIs in MSM PWH in a Male HIV Clinic in Mexico City.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

R Jeffrey EdwardsMedical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.ORCID 0000-0002-4392-8998
Abigail MohammedMedical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.
Leon-Omari LaviaMedical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.
Jonathan EdwardsMedical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.
Shiva VermaMedical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.
Saketh ReddyMedical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.ORCID 0000-0002-4884-1402
Gregory BoyceMedical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.ORCID 0000-0002-2434-4612
University of the West Indies · TT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyphilis among men who have sex with men (MSM) living with HIV is of public health concern, thus the objective of the study is to determine the correlates of prevalent syphilis infection in this population so that urgent interventions could be instituted.

methodsA cross-sectional study was conducted during the period September 2020-June 2021 among MSM who attended a large HIV Clinic in Trinidad. A questionnaire was administered to obtain socio-demographic data and correlates of prevalent syphilis and patients were screened for syphilis using the traditional algorithm. Descriptive and bivariate analyses were conducted and multivariable logistic regression factors was used to assess factors significantly associated with a syphilis diagnosis.

resultsTwo hundred and sixty four MSM were enrolled; age range 18-64 years, median age 33 years and 89 (34.4%) were actively bisexual. The prevalence of syphilis was 28% (74/264) and 89.2% (66/74) of these infections were asymptomatic. Multivariable logistic regression analysis showed that those patients who participated in sex with anonymous partners (OR 2.09; 95% CI, 1.03-4.26), those with a previous diagnosis of syphilis (OR 5.16; 95% CI, 1.03-25.83) and those who used marijuana in the last 12 months (OR 2.13; 95% CI, 1.14-3.96) were more likely to be diagnosed with syphilis.

conclusionThere is a high prevalence of asymptomatic syphilis among MSM living with HIV in Trinidad. Repeat episodes of syphilis and anonymous sex may play a role in the transmission dynamics of T pallidum infection in this population, thus urgent public health prevention interventions are warranted.

Indexed as

HIV InfectionsSexual and Gender MinoritiesSyphilisAdolescentAdultChinaCross-Sectional StudiesHomosexuality, MaleHumansMaleMiddle AgedPrevalenceRisk FactorsSexual BehaviorSurveys and QuestionnairesTrinidad and Tobago

Identifiers

PMID35358217
PMCPMC8970382
OpenAlexW4220850314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.