Evidence map›Paper›PMID 35358176›Full record

ArticlePLoS biology2022

The highways and byways of the brain.

Claus C Hilgetag, Basilis Zikopoulos

Abstract readComment
In one paragraph

Article in PLoS biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Artificial Intelligence Networks Combining Histopathology and Machine Learning Can Extract Axon Pathology in Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  2. Article
  3. Review
  4. Evolution and adoption of contributor role ontologies and taxonomies.Learned publishing : journal of the Association of Learned and Professional Society Publishers · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Claus C HilgetagInstitute of Computational Neuroscience, University Medical Center Eppendorf, Hamburg University, Hamburg, Germany.ORCID 0000-0003-2129-8910
Basilis ZikopoulosDepartment of Health Sciences, Boston University, Boston, Massachusetts, United States of America.

Funding

Organization and Circuit Interactions of Thalamocortical Attentional Networks in Health and DiseaseR01MH118500 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Arash Yazdanbakhsh, Vasileios Zikopoulos · 2019 to 2026
$4.8M
NIMH NIH HHS R01 MH118500
6 · The paper itself

Abstract

Brain functions rely on the communication network formed by axonal fibers. However, the number of axons connecting different brain regions is unknown. A study in PLoS Biology addresses this question and finds that most areas of the human cerebral cortex are linked by an astoundingly small number of fibers.

Indexed as

AxonsBrainCerebral CortexHumans

Identifiers

PMID35358176
PMCPMC9004754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.