Evidence map›Paper›PMID 35357768›Full record

ArticleJournal of applied clinical medical physics2022

Automated conversion of Millennium-120 VMAT plans to HDMLC geometry: Software development and treatment of first patients.

Ray Yang, Michael Lamey, Leigh Bartha, Michael Johnston, Alexandra Warburton, Dawn Gillund, Nathan Becker

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ray YangDepartment of Medical Physics, BC Cancer - Centre for the Southern Interior, Kelowna, British Columbia, Canada.
Michael LameyDepartment of Medical Physics, BC Cancer - Centre for the Southern Interior, Kelowna, British Columbia, Canada.
Leigh BarthaDepartment of Radiation Therapy, BC Cancer - Centre for the Southern Interior, Kelowna, British Columbia, Canada.
Michael JohnstonDepartment of Radiation Therapy, BC Cancer - Centre for the Southern Interior, Kelowna, British Columbia, Canada.
Alexandra WarburtonDepartment of Radiation Therapy, BC Cancer - Centre for the Southern Interior, Kelowna, British Columbia, Canada.
Dawn GillundDepartment of Radiation Therapy, BC Cancer - Centre for the Southern Interior, Kelowna, British Columbia, Canada.
Nathan BeckerDepartment of Medical Physics, BC Cancer - Centre for the Southern Interior, Kelowna, British Columbia, Canada.
Interior Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide plan backup resiliency for patients treated on a solitary high definition multileaf collimator (HDMLC) linac by developing a fully integrated Eclipse script, which converts patient plans initially optimized on Millennium-120 (M120) MLC to dosimetrically equivalent leaf motions for delivery on HDMLC. In the event of HDMLC machine downtime, affected patients can be transferred to Millennium-120 units, and their backup plan delivered without delay.

methodsWrite-enabled Eclipse scripting is leveraged to generate HDMLC treatment fields with control points parameterized to mimic apertures of an existing Millennium-120 VMAT plan. Non-parity between intermediate control point gantry angles of script generated arcs relative to VMAT is reconciled through an interpolation subroutine to correct for the apertures and monitor units that would have existed at intermediate angles. Differences in dosimetric leaf gap are corrected by displacing the subset of leaves undergoing dynamic motion. A nominal change to plan normalization corrects for remaining discrepancies between beam models.

resultsOver 220 non-SABR VMAT patients were treated on a solitary HDMLC linac with plans converted using the developed script. All have undergone streamlined RO review and physics quality assurance (QA), where the converted plan replicates the original leaf patterns, representing a minor dosimetric perturbation. Analyzing a subset of converted plans delivered at four anatomical sites, on average 99.3% of points pass the 1%/1 mm gamma criterion. Dose-volume histograms between the original and converted plans are in excellent agreement. ArcCheck measurements comparing delivery of the converted HDMLC plan to the calculated M120 dose distribution averaged a gamma pass rate of 99.4% (95.2%) at a 3%/3 mm (2%/2 mm) criterion. The conversion process takes 30 s to run, avoids errors in exporting/re-importing, and generates leaf motions deliverable within machine limits.

conclusionThe methodology developed for automated plan conversion helped maximize the utilization of a solitary HDMLC linac, while preserving backup interoperability with minimal overhead.

Indexed as

Radiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedHumansParticle AcceleratorsRadiotherapy DosageSoftwareautomationbackupHDMLCinteroperabilityscripting

Identifiers

PMID35357768
PMCPMC9195034
OpenAlexW4220671694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.