Evidence map›Paper›PMID 35357724›Full record

Observational studyActa paediatrica (Oslo, Norway : 1992)2022

Birthweight z-score and fat-free mass at birth predict body composition at 3 years in Danish children born from obese mothers.

Nanna R Berglund, Jack I Lewis, Kim F Michaelsen, Christian Mølgaard, Kristina M Renault, Emma M Carlsen

Abstract readObservational Study
In one paragraph

Observational study in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nanna R BerglundDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark.ORCID 0000-0002-8325-1029
Jack I LewisDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark.ORCID 0000-0001-9483-912X
Kim F MichaelsenDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark.
Christian MølgaardDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark.
Kristina M RenaultDepartment of Obstetrics and Gynecology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Emma M CarlsenDepartment of Pediatrics, Hvidovre Hospital, Copenhagen University Hospital, Hvidovre, Denmark.

Funding

Aase and Ejner Danielsens FoundationAugustinus FoundationUniversity of Copenhagen Excellence Program
6 · The paper itself

Abstract

aimWe investigated associations between newborn body composition and anthropometry and body composition at 3 years in Danish children born from obese mothers.

methodsAnalyses are based on data from the observational cohort study SKOT II (SKOT; small children's diet and well-being (Danish)). Body composition at birth and at 3 years was assessed by dual-energy X-ray absorptiometry (DXA) scans and bioelectrical impedance analysis (BIA), respectively. Multiple linear regression models were applied to determine associations between newborn body composition and anthropometry and body composition at 3 years.

resultsBirthweight z-score (BWZ) was positively associated with fat-free mass (FFM), height, fat-free mass index (FFMI), fat mass (FM) and fat mass index (FMI) at 3 years. Newborn FFM was positively associated with FFM, height, FFMI and FM at 3 years, and positive trends were seen between newborn FM and FM and FMI at 3 years.

conclusionWe showed that infants born with a higher BWZ go on to be taller at 3 years. They also grow to be heavier, to which FM and FFM both contribute, independently of linear growth. Additionally, it seems that FFM tracks into early childhood, thus supporting intrauterine programming of later health.

Indexed as

Body CompositionMothersAbsorptiometry, PhotonBirth WeightBody Mass IndexChildChild, PreschoolDenmarkElectric ImpedanceFemaleHumansInfantInfant, NewbornObesitybioelectrical impedance analysisdual-energy X-ray absorptiometryfat-free massfat massmaternal obesityoffspring body composition

Identifiers

PMID35357724
PMCPMC9322285

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.