Evidence map›Paper›PMID 35357661›Full record

ArticleApplied biochemistry and biotechnology2022

Hydrophilized Ultrafiltration Membranes Synthesized from Acrylic Acid Grafted Polyethersulfone for Downstream Processing of Therapeutic Insulin and Cobalamin.

N Shiva Prasad, N Lakshmi Gayatri, B Naga Sandhya, S Kalyani, Suresh K Bhargava, Sundergopal Sridhar

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied biochemistry and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

N Shiva PrasadMembrane Separations Laboratory, Process Engineering, and Technology Transfer Division, CSIR - Indian Institute of Chemical Technology, Hyderabad, 500007, India.
N Lakshmi GayatriMembrane Separations Laboratory, Process Engineering, and Technology Transfer Division, CSIR - Indian Institute of Chemical Technology, Hyderabad, 500007, India.
B Naga SandhyaMembrane Separations Laboratory, Process Engineering, and Technology Transfer Division, CSIR - Indian Institute of Chemical Technology, Hyderabad, 500007, India.
S KalyaniMembrane Separations Laboratory, Process Engineering, and Technology Transfer Division, CSIR - Indian Institute of Chemical Technology, Hyderabad, 500007, India.
Suresh K BhargavaRoyal Melbourne Institute of Technology (RMIT), Melbourne, VIC, 3001, Australia.
Sundergopal SridharMembrane Separations Laboratory, Process Engineering, and Technology Transfer Division, CSIR - Indian Institute of Chemical Technology, Hyderabad, 500007, India. sridhar11in@yahoo.com.
Indian Institute of Chemical Technology · INAcademy of Scientific and Innovative Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study focuses on synthesis of novel high-performance acrylic acid (AA) grafted polyethersulfone (PES) ultrafiltration (UF) membranes for purification of small therapeutic biomolecules such as urea, insulin, and cobalamin. The membranes were indigenously synthesized by adding polyethylene glycol (PEG) of 6 kDa M.Wt. as a pore former and subsequent grafting of AA using 2 to 6 wt.% concentrations under UV-induced photo grafting. Scanning electron microscopy reveals that the PEG additive profoundly influences the pore density on the membrane surface. FTIR spectra confirm the graft polymerization of AA with the PES substrate. Separation performance of the grafted membranes was evaluated to establish the trade-off between the degree of grafting and MWCO. From the experimental results, the pure water flux (PWF) of 6% grafted PES membrane was enhanced from 8.5 (PES [0] [6]) to 18.20 l m

Indexed as

InsulinsUltrafiltrationAcrylatesMembranes, ArtificialPolyethylene GlycolsPolymersSulfonesUreaVitamin B 12Acrylatesacrylic acidInsulinsMembranes, Artificialpolyether sulfonePolyethylene GlycolsPolymersSulfonesUreaVitamin B 12Acrylic acidPolyethersulfonePolyethylene glycolUltrafiltration membraneUV grafting

Identifiers

PMID35357661
PMCPMC9270308
OpenAlexW4220996425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.