Evidence map›Paper›PMID 35357557›Full record

ArticleJournal of neurology2022

Endovascular treatment of ischemic stroke due to isolated internal carotid artery occlusion: ETIS registry data analysis.

Adrien Ter Schiphorst, Roxane Peres, Cyril Dargazanli, Raphaël Blanc, Benjamin Gory, Sébastien Richard, Gaultier Marnat, Igor Sibon, Benoit Guillon, Romain Bourcier and 9 more

Abstract read
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In one paragraph

Article in Journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 1 country.

Adrien Ter SchiphorstDepartment of Neurology, CHRU Gui de Chauliac, University Hospital of Montpellier, 80 Avenue Augustin Fliche, 34295, Montpellier, France.
Roxane PeresDepartment of Neurology, Fondation Rothschild Hospital, Paris, France.
Cyril DargazanliDepartment of Interventional Neuroradiology, CHRU Gui de Chauliac, University Hospital of Montpellier, Montpellier, France.
Raphaël BlancDepartment of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France.
Benjamin GoryDepartment of Diagnostic and Therapeutic Neuroradiology, INSERM U1254, Université de Lorraine, CHRU-Nancy, 54000, Nancy, France.
Sébastien RichardDepartment of Neurology, Stroke Unit, INSERM U1116, 54000, Nancy, France.
Gaultier MarnatDepartment of Diagnostic and Interventional Neuroradiology, University Hospital of Bordeaux, Bordeaux, France.
Igor SibonDepartment of Neurology, Stroke Center, University Hospital of Bordeaux, Bordeaux, France.
Benoit GuillonDepartment of Neurology, University Hospital of Nantes, Nantes, France.
Romain BourcierDepartment of Neuroradiology, University Hospital of Nantes, Nantes, France.
Christian DenierDepartment of Neurology, CHU Bicêtre, Le Kremlin Bicêtre, France.
Laurent SpelleDepartment of Interventional Neuroradiology, CHU Bicêtre, Le Kremlin Bicêtre, France.
Julien LabreucheULR 2694-METRICS: Évaluation des Technologies de Santé et des Pratiques Médicales, Université de Lille, CHU Lille, 59000, Lille, France.
Arturo ConsoliDepartment of Neuroradiology, Foch Hospital, Suresnes, France.
Bertrand LapergueDepartment of Neurology, Foch Hospital, Suresnes, France.
Vincent CostalatDepartment of Interventional Neuroradiology, CHRU Gui de Chauliac, University Hospital of Montpellier, Montpellier, France.
Michael ObadiaDepartment of Neurology, Fondation Rothschild Hospital, Paris, France.
Caroline ArquizanDepartment of Neurology, CHRU Gui de Chauliac, University Hospital of Montpellier, 80 Avenue Augustin Fliche, 34295, Montpellier, France. c-arquizan@chu-montpellier.fr.ORCID http://orcid.org/0000-0001-7347-1039
ETIS Registry Investigators
Assistance Publique – Hôpitaux de Paris · FRHôpital Foch · FRHôpital Gui de Chauliac · FRInserm · FRCentre Hospitalier Universitaire de Nantes · FRFondation de Rothschild · FRUniversité de Lille · FRCentre Hospitalier Universitaire de Montpellier · FRInstitut de Neurosciences Cognitives et Intégratives d’Aquitaine · FRUniversité de Bordeaux · FRBicêtre Hospital · FRCentre Hospitalier Régional et Universitaire de Nancy · FRCentre Hospitalier Universitaire de Bordeaux · FRImagerie Adaptative Diagnostique et Interventionnelle · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe best treatment for acute ischemic stroke (AIS) due to isolated cervical internal carotid artery occlusion (CICAO) (i.e., without associated occlusion of the circle of Willis) is still unknown. In this study, we aimed to describe EVT safety and clinical outcome in patients with CICAO.

methodsWe analyzed data of all consecutive patients, included in the Endovascular Treatment in Ischemic Stroke (ETIS) Registry between 2013 and 2020, who presented AIS and proven CICAO on angiogram and underwent EVT. We assessed carotid recanalization, procedural complications, National Institutes of Health Stroke Scale (NIHSS) at 24 h post-EVT, and 3-month favorable outcome (modified Rankin Scale, mRS ≤ 2 or equal to the pre-stroke value).

resultsForty-five patients were included (median age: 70 years; range: 62-82 years). The median NIHSS before EVT was 14 (9-21). Carotid stenting was performed in 23 (51%) patients. Carotid recanalization at procedure end and on control imaging was observed in 37 (82%) and 29 (70%) patients, respectively. At day 1 post-EVT, the NIHSS remained stable or decreased in 25 (60%) patients; 12 (29%) patients had early neurologic deterioration (NIHSS ≥ 4 points). The rate of procedural complications was 36%, including stent thrombosis (n = 7), intracranial embolism (n = 7), and symptomatic intracranial hemorrhage (n = 1). At 3 months, 18 (40%) patients had a favorable outcome, and 10 (22%) were dead.

conclusionOur study suggests that EVT in AIS patients with moderate/severe initial deficit due to CICAO led to high rate of recanalization at day 1, and a 40% rate of favorable outcome at 3 months. There was a high rate of procedural complication which is of concern. Randomized controlled trials assessing the superiority of EVT in patients with CICAO and severe deficits are needed.

Indexed as

Brain IschemiaCarotid Artery DiseasesEndovascular ProceduresIschemic StrokeStrokeThrombosisAgedCarotid Artery, InternalData AnalysisHumansRegistriesThrombectomyTreatment OutcomeCervicalStentStrokeThrombectomyThrombolysis

Identifiers

PMID35357557
OpenAlexW4220972340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.