Evidence map›Paper›PMID 35357532›Full record

ArticleNeuroradiology2022

T2 hypointense signal discovered incidentally at the posterior edge of the adenohypophysis on MRI: its prevalence and morphology and their relationship to age.

Aiko Gobara, Takashi Katsube, Hiroya Asou, Rika Yoshida, Takeshi Yoshizako, Hajime Kitagaki

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Article in Neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Aiko GobaraDepartment of Radiology, Shimane University Faculty of Medicine, 89-1 Enyacho, P.O. Box 00693-8501, Izumo, Japan. aikogobara@gmail.com.ORCID http://orcid.org/0000-0002-6031-2810
Takashi KatsubeDepartment of Radiology, Shimane University Faculty of Medicine, 89-1 Enyacho, P.O. Box 00693-8501, Izumo, Japan.
Hiroya AsouDepartment of Radiology, Shimane University Faculty of Medicine, 89-1 Enyacho, P.O. Box 00693-8501, Izumo, Japan.
Rika YoshidaDepartment of Radiology, Shimane University Faculty of Medicine, 89-1 Enyacho, P.O. Box 00693-8501, Izumo, Japan.
Takeshi YoshizakoDepartment of Radiology, Shimane University Faculty of Medicine, 89-1 Enyacho, P.O. Box 00693-8501, Izumo, Japan.
Hajime KitagakiDepartment of Radiology, Shimane University Faculty of Medicine, 89-1 Enyacho, P.O. Box 00693-8501, Izumo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeT2 hypointense signal at the posterior edge of the adenohypophysis (T2HSPA) on magnetic resonance imaging (MRI) is incidentally encountered. We aimed to investigate the prevalence and morphology of T2HSPA and their relationship to age.

methodsA total of 212 cases between 3 and 88 years old were examined. Sagittal T2-weighted image (T2WI) was evaluated for the presence of T2HSPA, which classified by its morphology into two types (belt-like or nodal). The Wilcoxon rank sum test and chi-square test were used to evaluate the differences between the groups. The T2HSPA was extracted by ImageJ software and measured as a cross-sectional area (CSA) quantitatively by threshold setting. We examined the relationship between CSA of T2HSPA and age, and Spearman's correlation coefficients were used for statistical analysis.

resultsOf the 212 cases, 80 (37.7%) were identified with T2HSPA. The groups with T2HSPA were significantly younger than the groups without it (p = .01). Groups with belt-like T2HSPA were significantly younger than the groups with nodal T2HSPA (p = .01). There was a weak negative correlation between CSA of T2HSPA and age (p = .02).

conclusionT2HSPAs were incidentally detected in 37.7% of all cases, tended to be more common in younger cases, and their morphology was related to age. They seem to have little clinical significance as they tend to decrease in size with age.

Indexed as

Central Nervous System CystsPituitary Gland, AnteriorAdolescentAdultAgedAged, 80 and overChildChild, PreschoolHumansMagnetic Resonance ImagingMiddle AgedPrevalenceYoung AdultMRIPars intermediaPituitaryRathke’s cleft cystT2-weighted image

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PMID35357532

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