Evidence map›Paper›PMID 35357272›Full record

ArticleRenal failure2022

The spectrum of renal diseases with lupus-like features: a single-center study.

Maliha Ahmed, Tanzy Love, Catherine Moore, Thu H Le, Jerome Jean-Gilles, Bruce Goldman, Hae Yoon Grace Choung

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maliha AhmedDepartment of Medicine, Division of Nephrology, University of Rochester Medical Center, Rochester, NY, USA.
Tanzy LoveDepartment of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA.
Catherine MooreDepartment of Medicine, Division of Nephrology, University of Rochester Medical Center, Rochester, NY, USA.
Thu H LeDepartment of Medicine, Division of Nephrology, University of Rochester Medical Center, Rochester, NY, USA.
Jerome Jean-GillesDepartment of Pathology and Laboratory Medicine, Division of Renal Pathology and Electron Microscopy, University of Rochester Medical Center, Rochester, NY, USA.
Bruce GoldmanDepartment of Pathology and Laboratory Medicine, Division of Renal Pathology and Electron Microscopy, University of Rochester Medical Center, Rochester, NY, USA.
Hae Yoon Grace ChoungDepartment of Pathology and Laboratory Medicine, Division of Renal Pathology and Electron Microscopy, University of Rochester Medical Center, Rochester, NY, USA.ORCID 0000-0002-1741-3173
University of Rochester Medical Center · US

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Sally W Thurston · 1985 to 2026
$42.8M
NIEHS NIH HHS P30 ES001247
6 · The paper itself

Abstract

backgroundA subset of patients without overt systemic lupus erythematosus (SLE) present with biopsy findings typically seen in lupus nephritis (LN). Although a minority eventually develops SLE, many do not. It remains unclear how to classify or treat these patients. Our study attempted to further understand the clinical and pathological characteristics of cases with lupus-like nephritis (LLN).

methodsAmong 2700 native kidney biopsies interpreted at University of Rochester Medical Center (URMC) from 2010 to 2019, we identified 27 patients with biopsies showing lupus-like features (LL-fx) and 96 with LN. Of those with LL-fx, 17 were idiopathic LLN and 10 were associated with a secondary etiology (e.g., infection/drugs).

resultsAt the time of biopsy, the LLN-group tended to be slightly older (44

conclusionsLupus-like pathologic features are seen in a wide array of disease processes. The findings suggest that LLN may be a manifestation of an autoimmune process that overlaps with SLE.

Indexed as

Lupus Erythematosus, SystemicLupus NephritisRenal Insufficiency, ChronicBiopsyHumansMaleProteinuriaautoimmune diseasefull-house nephropathylupusLupus-like nephritislupus nephritis

Identifiers

PMID35357272
PMCPMC8979540
OpenAlexW4220944663

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.