ArticlemSystems2022
Distinct N and C Cross-Feeding Networks in a Synthetic Mouse Gut Consortium.
Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Revisiting gut microbiota-driven ammonia metabolism: from disease burden to physiological adaptation.Gut microbes · 2026Review
- The OMMGut microbes · 2026Review
- The Gut Microbiome Dependency Continuum in Drug Discovery: A Unified Pharmacology Framework Linking Clinical Drugs, Natural Products, and Engineered Microbial Therapeutics.Biotech (Basel (Switzerland)) · 2026Review
- Microbial interactions in facilitating antibiotic activity and resistance evolution.Applied and environmental microbiology · 2026Review
- Review
- Translating priority effects and niche engineering into rational microbiome therapeutics across the gut-lung axis.Frontiers in microbiology · 2026Review
- Article
- Revisiting nitrogen assimilation strategies in the mammalian gut: lessons from Enterobacteriaceae as pathobiont models and a challenge to the limitation paradigm.Archives of microbiology · 2025Review
- Designing synthetic microbial communities for enhanced anaerobic waste treatment.Applied and environmental microbiology · 2025Review
- Precision microbial regulation: Strategies for modulating GIT microbiota for host health.iMetaOmics · 2025Article
- Targeted prebiotic application of gluconic acid-containing oligosaccharides promotes Faecalibacterium growth through microbial cross-feeding networks.The ISME journal · 2025Article
- Nutrition ofEcoSal Plus · 2024Review
- Tuft cells in the intestine, immunity and beyond.Nature reviews. Gastroenterology & hepatology · 2024Review
- A cross-systems primer for synthetic microbial communities.Nature microbiology · 2024Review
- The detection and utilization of volatile metabolomics in Klebsiella pneumoniae by gas chromatography-ion mobility spectrometry.Scientific reports · 2024Article
- Emerging tools and best practices for studying gut microbial community metabolism.Nature metabolism · 2024Review
- Plasmid-encoded toxin defence mediates mutualistic microbial interactions.Nature microbiology · 2024Article
- Integrated multi-omics reveals the roles of cecal microbiota and its derived bacterial consortium in promoting chicken growth.mSystems · 2023Article
- Nutritional and host environments determine community ecology and keystone species in a synthetic gut bacterial community.Nature communications · 2023Article
- Cross-feeding in the gut microbiome: Ecology and mechanisms.Cell host & microbe · 2023Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The complex interactions between the gut microbiome and host or pathogen colonization resistance cannot be understood solely from community composition. Missing are causal relationships, such as metabolic interactions among species, to better understand what shapes the microbiome. Here, we focused on metabolic niches generated and occupied by the Oligo-Mouse-Microbiota (OMM) consortium, a synthetic community composed of 12 members that is increasingly used as a model for the mouse gut microbiome. Combining monocultures and spent medium experiments with untargeted metabolomics revealed broad metabolic diversity in the consortium, constituting a dense cross-feeding network with more than 100 pairwise interactions. Quantitative analysis of the cross-feeding network revealed distinct C and N food webs, highlighting the two
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.