Evidence map›Paper›PMID 35356815›Full record

ArticleBioactive materials2022

Multiple stimuli-responsive nanosystem for potent, ROS-amplifying, chemo-sonodynamic antitumor therapy.

JunJie Tang, Xiaoge Zhang, Lili Cheng, Yadong Liu, You Chen, Zhaozhong Jiang, Jie Liu

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

JunJie TangSchool of Biomedical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510006, China.
Xiaoge ZhangSchool of Biomedical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510006, China.
Lili ChengSchool of Biomedical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510006, China.
Yadong LiuSchool of Biomedical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510006, China.
You ChenSchool of Biomedical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510006, China.
Zhaozhong JiangFaculty of Arts and Sciences, Department of Biomedical Engineering, Integrated Science and Technology Center, Yale University, 600 West Campus Drive, West Haven, CT, 06516, United States.
Jie LiuSchool of Biomedical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510006, China.
Sun Yat-sen University · CNYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although sonodynamic therapy (SDT) is a promising non-invasive tumor treatment strategy due to its safety, tissue penetration depth and low cost, the hypoxic tumor microenvironment limits its therapeutic effects. Herein, we have designed and developed an oxygen-independent, ROS-amplifying chemo-sonodynamic antitumor therapy based on novel pH/GSH/ROS triple-responsive PEG-PPMDT nanoparticles. The formulated artemether (ART)/Fe

Indexed as

Chemodynamic therapyMRI imagingNanoparticlepH/GSH/ROS triple-ResponsiveSonodynamic therapy

Identifiers

PMID35356815
PMCPMC8935089
OpenAlexW4200474403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.