ArticleToxicology reports2022
Enhanced sensitivity of an Ah-receptor system in yeast through condition modification and use of mammalian modifiers.
Emmanuel Vazquez-Rivera, Brenda L Rojas, Patrick R Carney, Jose L Marrero-Valentin, Christopher A Bradfield
Open access · goldAbstract read
In one paragraphArticle in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
5 authors at 1 institution in 1 country.
Emmanuel Vazquez-RiveraMolecular and Environmental Toxicology Center, McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.
Brenda L RojasMolecular and Environmental Toxicology Center, McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.
Patrick R CarneyMolecular and Environmental Toxicology Center, McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.
Jose L Marrero-ValentinMolecular and Environmental Toxicology Center, McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.
Christopher A BradfieldMolecular and Environmental Toxicology Center, McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.
University of Wisconsin–Madison · US
Funding
UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6MMolecular & Environmental Toxicology Pre-& Postdoctoral Training ProgramT32ES007015 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER A BRADFIELD · 1985 to 2026
$11.5MTraining in Cancer Biology Training GrantT32CA009135 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SUGDEN, WILLIAM M. · 1985 to 2024
$10.4MINTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3MThe PAS Sensor Family and Human HealthR35ES028377 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI BRADFIELD, CHRISTOPHER A · 2017 to 2024
$6.7MIntegrated Training For Physician-ScientistsT32GM140935 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher, Jeniel E Nett · 2021 to 2026
$6.5MSummer Research Experience for Minority UndergraduatesR25ES020720 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER A BRADFIELD, Sean M. Ronnekleiv-Kelly · 2011 to 2026
$1.3MNCI NIH HHS P30 CA014520NCI NIH HHS T32 CA009135NIEHS NIH HHS R25 ES020720NIEHS NIH HHS R35 ES028377NIEHS NIH HHS T32 ES007015NIGMS NIH HHS T32 GM008692NIGMS NIH HHS T32 GM140935
6 · The paper itselfAbstract
Proteins, such as the Ah receptor (AHR), hold potential as sensors to detect ligands in environmental and biological samples, and may also serve as tools to regulate biosynthetic and industrial processes. The AHR is also a prototype system for the PAS superfamily that can sense and mediate adaptation to signals as diverse as light, voltage, oxygen and an array of small molecules. The yeast,
Indexed as
Ah receptorAssayLigandsPolycyclic aromatic hydrocarbonsReporterYeast
Identifiers
PMID35356645
PMCPMC8958262
OpenAlexW4226240891
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390