Evidence map›Paper›PMID 35356257›Full record

ArticleJournal of oncology2022

Ogt Demonstrated Conspicuous Clinical Significance in Cancers, from Pan-Cancer to Small-Cell Lung Cancer.

Deng Tang, Guo-Sheng Li, Ruo-Xiang Xu, Si-Yi Zhu, Jing Luo, Jin-Hua Zheng, Jun Liu, Hua-Song Lu, Mei-Hua Jin, Chong-Xi Bao and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Deng TangDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Guo-Sheng LiDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Ruo-Xiang XuDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Si-Yi ZhuDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Jing LuoDivision of Pulmonary and Critical Care Medicine, Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Jin-Hua ZhengDepartment of Pathology, The Affiliated Hospital of Guilin Medical University, Guilin 541000, China.
Jun LiuDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Hua-Song LuDivision of Pulmonary and Critical Care Medicine, Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Mei-Hua JinDepartment of Pathology, The Affiliated Hospital of Guilin Medical University, Guilin 541000, China.
Chong-Xi BaoDivision of Pulmonary and Critical Care Medicine, Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Jia TianDepartment of Pathology, The Affiliated Hospital of Guilin Medical University, Guilin 541000, China.
Wu-Sheng DengDivision of Pulmonary and Critical Care Medicine, Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Neng-Yong ZengDepartment of Respiratory and Critical Care Medicine, The Second People's Hospital of Qinzhou, Qinzhou 535000, China.
Hua-Fu ZhouDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.ORCID https://orcid.org/0000-0002-2267-3164
Jin-Liang KongDivision of Pulmonary and Critical Care Medicine, Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Gang ChenDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.ORCID https://orcid.org/0000-0003-2402-2987
Guangxi Medical University · CNGuilin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical progression of small-cell lung cancer (SCLC) remains pessimistic. The aim of the present study was to promote the understanding of the clinical significance and mechanism of O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) in SCLC. Wilcoxon tests, standardized mean difference (SMD), and Kruskal-Wallis tests were utilized to compare OGT level differences among the experimental and control groups. The univariate Cox regression analysis, Kaplan-Meier curves, and receiver operating characteristic curves were applied to determine OGT's clinical relevance in cancers. The Spearman correlation analysis and enrichment analysis were utilized to explore the underlying mechanisms of OGT in cancers. For the first time in the field, we provide an overview of OGT in 32 cancers using a large number of samples (

Identifiers

PMID35356257
PMCPMC8959957
OpenAlexW4226285443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.