ReviewFrontiers in oncology2022
Management of Motion and Anatomical Variations in Charged Particle Therapy: Past, Present, and Into the Future.
Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Implementation of VMAT-based lattice spatially fractionated radiation therapy (SFRT) across linac platforms: Practical considerations for QA and motion management.Journal of applied clinical medical physics · 2026Article
- Robustness of Tumor Control Against Intrafraction Patient Motion in Lung Stereotactic Body Radiation Therapy.Advances in radiation oncology · 2026Article
- Lung ion-fluoroscopy Guided Hadron therapy: LIGHT concept and proof-of-principle.Physics in medicine and biology · 2026Article
- Fluoroscopy-Guided Motion Management in Particle Therapy: Evolution, Challenges, and AI-Enabled Opportunities.Tomography (Ann Arbor, Mich.) · 2026Review
- Ionizing radiation acoustic beam localization: one step towards "proton surgery".medRxiv : the preprint server for health sciences · 2026Article
- Carbon ion radiotherapy and radiation-induced lung injury: clinical evidence, mechanistic insights, and future directions.Frontiers in oncology · 2026Review
- Signal-aware deep learning-based respiratory motion prediction for lung tumor management.Frontiers in oncology · 2026Article
- Advances in proton therapy technology and global clinical applications.Frontiers in oncology · 2026Review
- Towards ultra-fast treatments: large energy acceptance beam delivery systems and opportunities for proton beam therapy.Frontiers in oncology · 2026Review
- Emulating Clinical Workflow of Scintillator Array Dosimetry for FLASH Pencil-Beam Scanning Proton Therapy.International journal of radiation oncology, biology, physics · 2025Article
- Synthetic computed tomography techniques for adaptive proton therapy in head and neck cancers.Physics and imaging in radiation oncology · 2025Article
- Why are not all paediatric cancer patients treated with protons? A population-based report from Sweden, 2016-2023.Acta oncologica (Stockholm, Sweden) · 2025Article
- Proton GRID and LATTICE treatment planning techniques for clinical liver SFRT treatments.Physics in medicine and biology · 2025Article
- Imaging lung tumor motion using integrated-mode proton radiography-A phantom study towards tumor tracking in proton radiotherapy.Medical physics · 2025Article
- Current status and upcoming developments for online adaptive proton therapy enabling a closed feedback loop for near real-time adaptation.Frontiers in oncology · 2025Review
- Feasibility study of 4D-online monitoring of density gradients induced by lung cancer treatment using carbon ions.Frontiers in oncology · 2025Article
- Comparison of translation algorithms in determining maximum allowable CTV shifts for Real-Time Gated Proton Therapy (RGPT) robustness evaluation in prostate cancers.Journal of applied clinical medical physics · 2025Article
- Effect of breathing phase number on the 4D robust optimization for pancreatic cancer intensity modulated proton therapy.BMC cancer · 2024Article
- Motion-induced dose perturbations in photon radiotherapy and proton therapy measured by deformable liver-shaped 3D dosimeters in an anthropomorphic phantom.Physics and imaging in radiation oncology · 2024Article
- The rationale for a carbon ion radiation therapy facility in Australia.Journal of medical radiation sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The major aim of radiation therapy is to provide curative or palliative treatment to cancerous malignancies while minimizing damage to healthy tissues. Charged particle radiotherapy utilizing carbon ions or protons is uniquely suited for this task due to its ability to achieve highly conformal dose distributions around the tumor volume. For these treatment modalities, uncertainties in the localization of patient anatomy due to inter- and intra-fractional motion present a heightened risk of undesired dose delivery. A diverse range of mitigation strategies have been developed and clinically implemented in various disease sites to monitor and correct for patient motion, but much work remains. This review provides an overview of current clinical practices for inter and intra-fractional motion management in charged particle therapy, including motion control, current imaging and motion tracking modalities, as well as treatment planning and delivery techniques. We also cover progress to date on emerging technologies including particle-based radiography imaging, novel treatment delivery methods such as tumor tracking and FLASH, and artificial intelligence and discuss their potential impact towards improving or increasing the challenge of motion mitigation in charged particle therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.