Evidence map›Paper›PMID 35356150›Full record

ArticleCase reports in psychiatry2022

Levetiracetam-Induced Psychosis in the Setting of Intracranial Cavernomas.

Daniel Majarwitz, Mariam Dvalishvili, Irene Pastis

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel MajarwitzDepartment of Psychiatry and Behavioral Medicine, East Carolina University-Vidant Medical Center, Greenville, NC, USA.ORCID https://orcid.org/0000-0003-3044-0931
Mariam DvalishviliDepartment of Internal Medicine, East Carolina University-Vidant Medical Center, Greenville, NC, USA.ORCID https://orcid.org/0000-0001-8158-9731
Irene PastisDepartment of Psychiatry and Behavioral Medicine, East Carolina University-Vidant Medical Center, Greenville, NC, USA.ORCID https://orcid.org/0000-0003-1426-3226
Vidant Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Levetiracetam is a commonly used antiepileptic medication that has been associated with the development of psychosis. Cavernomas are vascular malformations that have been associated with psychosis as well, especially in the setting of hemorrhagic transformation. This case report describes a patient with cavernomas who developed psychotic symptoms after restarting her levetiracetam at a high dose (2000 mg twice a day) without gradual uptitration. Her symptoms improved upon the reduction of the levetiracetam as well as the initiation of paliperidone. This case highlights the importance of considering the biologic and medication-related factors for the development of psychosis, as well as the importance of gradual medication adjustments.

Identifiers

PMID35356150
PMCPMC8960016
OpenAlexW4220927140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.