SynthesisFrontiers in neuroscience2022
The Lamellar Cells of Vertebrate Meissner and Pacinian Corpuscles: Development, Characterization, and Functions.
Synthesis in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Exploratory Immunohistochemical Mapping of Mechanosensitivity-Associated Ion Channel Proteins in Terminal Glial Cells of Human Meissner and Pacinian Corpuscles.International journal of molecular sciences · 2026Article
- Pacinian Corpuscle-Inspired Strain Conversion Enables Ultrasensitive, Linear, and Broad-Range Piezoelectric Sensing for Cardiovascular Health Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Skin innervation and itsFrontiers in cellular neuroscience · 2026Review
- Autoantibodies against Components of Sensory Nerve Formations in the Intervertebral Disks and Adjacent Structures are Antigens Recognized by the Sera from Patients Affected by a New Variant of Endemic Pemphigus in El Bagre, Colombia.Dermatology practical & conceptual · 2025Article
- ACL Pacinian mechanoreceptors: Conceptualizing a vasoregulatory microtrauma healing function.Journal of experimental orthopaedics · 2025Article
- The role of skin hydration, skin deformability, and age in tactile friction and perception of materials.Scientific reports · 2025Article
- The inner core enables transient touch detection in the Pacinian corpuscle.Science advances · 2025Article
- Contributions and future potential of animal models for geroscience research on sensory systems.GeroScience · 2025Review
- Periarticular Proprioception: Analyzing the Three-Dimensional Structure of Corpuscular Mechanosensors in the Dorsal Part of the Scapholunate Ligament.Cells, tissues, organs · 2025Article
- Axonal and Glial PIEZO1 and PIEZO2 Immunoreactivity in Human Clitoral Krause's Corpuscles.International journal of molecular sciences · 2024Article
- Schwann Cells as Orchestrators of Nerve Repair: Implications for Tissue Regeneration and Pathologies.Cold Spring Harbor perspectives in biology · 2024Review
- Origin, identity, and function of terminal Schwann cells.Trends in neurosciences · 2024Review
- The mechanoreceptors in hatchling and adult Elasmobranch skin.microPublication biology · 2024Article
- Characterisation of GFAP-Expressing Glial Cells in the Dorsal Root Ganglion after Spared Nerve Injury.International journal of molecular sciences · 2023Article
- Skin-type-dependent development of murine mechanosensory neurons.Developmental cell · 2023Article
- Review
- Sensory signals of unloading in insects are tuned to distinguish leg slipping from load variations in gait: experimental and modeling studies.Journal of neurophysiology · 2022Article
- The intriguing perineurial cells - an updated overview of their origin, structure, functions and implication in pathology.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
- Description of trunk neural crest migration and peripheral nervous system formation in the Egyptian cobra Naja haje haje.Differentiation; research in biological diversityArticle
- The Human Mechanosensory Corpuscles: A New Schwann Cell Localization of the Wilms' Tumor Protein WT1.The journal of histochemistry and cytochemistry : official journal of the Histochemistry SocietyArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensory corpuscles, or cutaneous end-organ complexes, are complex structures localized at the periphery of Aβ-axon terminals from primary sensory neurons that primarily work as low-threshold mechanoreceptors. Structurally, they consist, in addition to the axons, of non-myelinating Schwann-like cells (terminal glial cells) and endoneurial- and perineurial-related cells. The terminal glial cells are the so-called lamellar cells in Meissner and Pacinian corpuscles. Lamellar cells are variably arranged in sensory corpuscles as a "coin stack" in the Meissner corpuscles or as an "onion bulb" in the Pacinian ones. Nevertheless, the origin and protein profile of the lamellar cells in both morphotypes of sensory corpuscles is quite similar, although it differs in the expression of mechano-gated ion channels as well as in the composition of the extracellular matrix between the cells. The lamellar cells have been regarded as supportive cells playing a passive role in the process of genesis of the action potential, i.e., the mechanotransduction process. However, they express ion channels related to the mechano-electric transduction and show a synapse-like mechanism that suggest neurotransmission at the genesis of the electrical action potential. This review updates the current knowledge about the embryonic origin, development modifications, spatial arrangement, ultrastructural characteristics, and protein profile of the lamellar cells of cutaneous end-organ complexes focusing on Meissner and Pacinian morphotypes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.