Evidence map›Paper›PMID 35355712›Full record

ArticleFrontiers in pharmacology2022

An Optimized Two-Herb Chinese Food as Medicine Formula Reduces Cisplatin-Induced Nephrotoxicity in the Treatment of Lung Cancer in Mice.

Le Shi, Yang Shu, Xiangdong Hu, Waheed Akram, Jun Wang, Shuang Dong, Biaobiao Luo, Jiuliang Zhang, Sheng Hu, Xiaohua Li and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Le ShiLaboratory of Natural Medicine and Molecular Engineering, College of Plant Science and Technology, National and Local Joint Engineering Research Center for Medicinal Plant Breeding and Cultivation, Hubei Provincial Engineering Research Center for Medicinal Plants, Innovation Academy of International Traditional Chinese Medicinal Materials, Huazhong Agricultural University, Wuhan, China.
Yang ShuLaboratory of Natural Medicine and Molecular Engineering, College of Plant Science and Technology, National and Local Joint Engineering Research Center for Medicinal Plant Breeding and Cultivation, Hubei Provincial Engineering Research Center for Medicinal Plants, Innovation Academy of International Traditional Chinese Medicinal Materials, Huazhong Agricultural University, Wuhan, China.
Xiangdong HuLaboratory of Natural Medicine and Molecular Engineering, College of Plant Science and Technology, National and Local Joint Engineering Research Center for Medicinal Plant Breeding and Cultivation, Hubei Provincial Engineering Research Center for Medicinal Plants, Innovation Academy of International Traditional Chinese Medicinal Materials, Huazhong Agricultural University, Wuhan, China.
Waheed AkramInstitute of Agricultural Sciences, University of the Punjab, Lahore, Pakistan.
Jun WangHubei Cancer Hospital, Wuhan, China.
Shuang DongHubei Cancer Hospital, Wuhan, China.
Biaobiao LuoLaboratory of Natural Medicine and Molecular Engineering, College of Plant Science and Technology, National and Local Joint Engineering Research Center for Medicinal Plant Breeding and Cultivation, Hubei Provincial Engineering Research Center for Medicinal Plants, Innovation Academy of International Traditional Chinese Medicinal Materials, Huazhong Agricultural University, Wuhan, China.
Jiuliang ZhangCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.
Sheng HuHubei Cancer Hospital, Wuhan, China.
Xiaohua LiLaboratory of Natural Medicine and Molecular Engineering, College of Plant Science and Technology, National and Local Joint Engineering Research Center for Medicinal Plant Breeding and Cultivation, Hubei Provincial Engineering Research Center for Medicinal Plants, Innovation Academy of International Traditional Chinese Medicinal Materials, Huazhong Agricultural University, Wuhan, China.
Xuebo HuLaboratory of Natural Medicine and Molecular Engineering, College of Plant Science and Technology, National and Local Joint Engineering Research Center for Medicinal Plant Breeding and Cultivation, Hubei Provincial Engineering Research Center for Medicinal Plants, Innovation Academy of International Traditional Chinese Medicinal Materials, Huazhong Agricultural University, Wuhan, China.
Huazhong Agricultural University · CNUniversity of the Punjab · PKHubei Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy is considered a most effective way to treat cancer. However, it is very common that chemotherapy causes unbearable mental and physical side effects to cancer patients, which ultimately reduces the patients' confidence of overcoming diseases and compromises the treatment of chemotherapy. Cisplatin (DDP), a widely used anticancer agent for various types of cancers, also damages nontumor cells and tissues, which are mostly related to the activation of the inflammation pathway. Previously, we have discovered a few rational formulas of food as medicine materials that reduced systemic inflammation in

Indexed as

cancerChinese herbal medicinecisplatininflammationnephrotoxicity

Identifiers

PMID35355712
PMCPMC8959097
OpenAlexW4220997059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.