Evidence map›Paper›PMID 35355692›Full record

ArticleRevista panamericana de salud publica = Pan American journal of public health2022

Ultrasensitive molecular tests for

Mariana Aschar, Maria Carmen A Sanchez, Maria de Jesus Costa-Nascimento, Maria de Lourdes R N Farinas, Angélica D Hristov, Giselle F M C Lima, Juliana Inoue, José E Levi, Silvia M Di Santi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista panamericana de salud publica = Pan American journal of public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mariana AscharFaculdade de Medicina Universidade de São Paulo São Paulo Brazil Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Maria Carmen A SanchezInstituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo São Paulo Brazil Instituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Maria de Jesus Costa-NascimentoSecretaria de Estado da Saúde de São Paulo/Instituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo São Paulo Brazil Secretaria de Estado da Saúde de São Paulo/Instituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Maria de Lourdes R N FarinasFaculdade de Medicina Universidade de São Paulo São Paulo Brazil Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Angélica D HristovFaculdade de Medicina Universidade de São Paulo São Paulo Brazil Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Giselle F M C LimaFaculdade de Medicina Universidade de São Paulo São Paulo Brazil Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Juliana InoueFaculdade de Medicina Universidade de São Paulo São Paulo Brazil Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
José E LeviInstituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo São Paulo Brazil Instituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Silvia M Di SantiSecretaria de Estado da Saúde de São Paulo/Instituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo São Paulo Brazil Secretaria de Estado da Saúde de São Paulo/Instituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate molecular tools to detect low-level parasitemia and the five species of Methods: We evaluated 145 blood samples from patients who tested positive by nested polymerase chain reaction (nPCR), from asymptomatic individuals and from the WHO Global Malaria Programme/United Kingdom National External Quality Assessment Service. Samples were assayed using the genus-specific RealStar Results: The levels of parasitemia ranged from 1 to 518 000 parasites/µL, depending on the species. Compared with nPCR, alt-S&T had a sensitivity of 100%, except for identifying Conclusions: The alt-Gen and alt-S&T assays are suitable for detecting submicroscopic infections for distinct epidemiological purposes, such as for use in surveys and reference laboratories, and screening in blood banks, which will contribute to global efforts to eliminate malaria.

Indexed as

MalariaPlasmodiumreal-time polymerase chain reaction

Identifiers

PMID35355692
PMCPMC8959250
OpenAlexW4220921785

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.