Evidence map›Paper›PMID 35355673›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2022

Risk factors for lymph node metastasis and indication of local resection in duodenal neuroendocrine tumors.

Eisuke Nakao, Ken Namikawa, Toshiaki Hirasawa, Kaoru Nakano, Yoshitaka Tokai, Shoichi Yoshimizu, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiyuki Yoshio, Souya Nunobe and 1 more

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Eisuke NakaoDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0002-6214-5673
Ken NamikawaDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.
Toshiaki HirasawaDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.
Kaoru NakanoDepartment of Pathology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.
Yoshitaka TokaiDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0002-3370-4405
Shoichi YoshimizuDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.
Yusuke HoriuchiDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0001-8116-8152
Akiyoshi IshiyamaDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0002-7626-645X
Toshiyuki YoshioDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0002-6546-0329
Souya NunobeDepartment of Gastroenterological Surgery Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.
Junko FujisakiDepartment of Gastroenterology Cancer Institute Hospital, Japanese Foundation for Cancer Research Tokyo Japan.
Japanese Foundation For Cancer Research · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: The risk factors for lymph node metastasis (LNM) of duodenal neuroendocrine tumors (DNETs) are not well identified, and a definitive standard of treatment for DNETs has not been established. In this study, we aimed to identify the risk factors for LNM and establish the indication of local resection for DNETs. Methods: We retrospectively reviewed 55 patients with 60 non-ampullary and nonfunctional DNETs. We evaluated the risk factors for LNM and compared the outcomes between endoscopic resection (ER) for DNETs <5 mm and laparoscopy and endoscopy cooperative surgery (LECS) for DNETs ≥5 mm. Results: LNM was present in four (8.7%) patients. Univariate analysis revealed that tumor size ≥10 mm, positive lymphovascular invasion (LVI), and 0-Is morphology were significantly associated with LNM ( Conclusions: Tumor size ≥10 mm, positive LVI, and 0-Is morphology were significant risk factors for LNM. We demonstrated that ER is feasible and could be safely applied for DNETs <5 mm, and LECS could be applied for DNETs 5-10 mm in size.

Indexed as

duodenal neuroendocrine tumorsendoscopic resectionlaparoscopy and endoscopy cooperative surgerylymph node metastasis

Identifiers

PMID35355673
PMCPMC8938752
OpenAlexW4212962835

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.