Evidence map›Paper›PMID 35355659›Full record

ArticleRespirology case reports2022

Humoral immune response in healthcare workers after two doses of a BNT162b2 mRNA vaccine in Yucatan, Mexico.

Esperanza Figueroa-Hurtado, Diana Lizbeth Ortíz-Farias, Isabel Sada-Ovalle, Sandra Yareth Maldonado-Ortíz, Jorge Arturo Valdivieso-Jiménez, Arturo Cortes-Telles

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Esperanza Figueroa-HurtadoDepartamento de Neumología y Cirugía de Tórax Hospital Regional de Alta Especialidad de la Península de Yucatán Mérida Mexico.ORCID https://orcid.org/0000-0003-1388-0572
Diana Lizbeth Ortíz-FariasDepartamento de Neumología y Cirugía de Tórax Hospital Regional de Alta Especialidad de la Península de Yucatán Mérida Mexico.ORCID https://orcid.org/0000-0002-3212-1929
Isabel Sada-OvalleDepartamento de Fisiología, Facultad de Medicina Universidad Autónoma de San Luis Potosí San Luis Potosi Mexico.ORCID https://orcid.org/0000-0001-7769-7625
Sandra Yareth Maldonado-OrtízUnidad de Cuidados Intensivos, Hospital Regional de Alta Especialidad de la Península de Yucatán Mérida Mexico.ORCID https://orcid.org/0000-0003-2338-2841
Jorge Arturo Valdivieso-JiménezUnidad de Atención COVID-19 Hospital Regional de Alta Especialidad de la Península de Yucatán Mérida Mexico.ORCID https://orcid.org/0000-0003-1824-8621
Arturo Cortes-TellesDepartamento de Neumología y Cirugía de Tórax Hospital Regional de Alta Especialidad de la Península de Yucatán Mérida Mexico.ORCID https://orcid.org/0000-0002-5322-5604
Hospital Regional de Alta Especialidad del Bajío · MXAutonomous University of San Luis Potosí · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as well as the host immune response after vaccination and viral infection have shown to be highly heterogeneous. This is a case series study analysing humoral immune response and vaccination side effects after two doses of a BNT162b2 mRNA among healthcare workers (HCWs) in Mexico. All participants were scheduled for their two doses of mRNA BNT162b2 vaccine and provided information through a questionnaire: demographic characteristics, antibody serum titres and vaccination-related side effects. Blood samples were obtained for serology testing after the first and second doses of vaccine. No serious adverse effects due to vaccination were reported; nonetheless, non-medical HCWs reported more side effects after the second dose. The previous infection with SARS-CoV-2 boosted immune response after receiving the first vaccination (roughly 30 times higher than those without previous infection); nonetheless, after the second dose, the immune response did not show a higher titre as might be expected.

Indexed as

COVID‐19humoral immunityimmune responsevaccine

Identifiers

PMID35355659
PMCPMC8938684
OpenAlexW4220773045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.