Evidence map›Paper›PMID 35355622›Full record

ArticleInfection and drug resistance2022

The Utility of Nonroutine Intraocular Fluid Polymerase Chain Reaction for Uveitis in Indonesia.

Ikhwanuliman Putera, Mei Riasanti, Lukman Edwar, Made Susiyanti, Ratna Sitompul, Yulia Aziza, Priscilla Jessica, Andriansjah Rukmana, Andi Yasmon, Rina La Distia Nora

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Polymerase chain reaction test for diagnosis of infectious uveitis.International journal of retina and vitreous · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ikhwanuliman PuteraDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.
Mei RiasantiDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.
Lukman EdwarDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.
Made SusiyantiDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.
Ratna SitompulDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.
Yulia AzizaDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.
Priscilla JessicaDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.
Andriansjah RukmanaDepartment of Microbiology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Andi YasmonDepartment of Microbiology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Rina La Distia NoraDepartment of Ophthalmology, Faculty of MedicineUniversitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital, Jakarta, Indonesia.ORCID 0000-0002-7026-5341
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo · IDErasmus MC · NLUniversity of Indonesia · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the utility of nonroutine polymerase chain reaction analysis of intraocular fluid to guide the diagnosis of infectious uveitis. Patients and Methods: A retrospective cohort study was conducted by reviewing medical record data from intraocular fluid samples of uveitis patients who underwent single-plex real-time polymerase chain reaction analysis at the Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Kirana Eye Hospital between January 2014 and December 2018. Results: The positivity rate of nonroutine polymerase chain reaction analysis was 17.2%. The vitreous sample tended to show a higher positive outcome (28.6%) than the aqueous sample (16.2%), even though the outcome was not statistically significant. Conclusion: Nonroutine polymerase chain reaction analysis of intraocular fluid among a cohort of Indonesian patients demonstrated low positivity. The sensitivity and specificity of nonroutine single-plex polymerase chain reaction could not be estimated due to limitations such as lost to follow-up patients and incomplete monitoring data. The use of multiplex polymerase chain reaction in the future may be beneficial in our setting.

Indexed as

aqueous humorepidemiologyinfectionMycobacterium tuberculosisocular inflammationvitreous humor

Identifiers

PMID35355622
PMCPMC8958196
OpenAlexW4220872829

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.